Evidence map›Paper›PMID 39286492›Full record

ArticleiScience2024

Metagenomic changes in response to antibiotic treatment in severe orthopedic trauma patients.

Afroditi Kouraki, Amy S Zheng, Suzanne Miller, Anthony Kelly, Waheed Ashraf, Davide Bazzani, Angela Bonadiman, Guendalina Tonidandel, Mattia Bolzan, Amrita Vijay and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Afroditi KourakiAcademic Unit of Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.
Amy S ZhengAcademic Unit of Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.
Suzanne MillerAcademic Unit of Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.
Anthony KellyAcademic Unit of Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.
Waheed AshrafAcademic Unit of Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.
Davide BazzaniPrebiomics srl, 38123 Trento, Italy.
Angela BonadimanPrebiomics srl, 38123 Trento, Italy.
Guendalina TonidandelPrebiomics srl, 38123 Trento, Italy.
Mattia BolzanPrebiomics srl, 38123 Trento, Italy.
Amrita VijayAcademic Unit of Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.
Jessica NightingaleAcademic Unit of Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.
Cristina MenniDepartment of Twin Research, King's College London, London SE1 7EH, UK.
Benjamin J OllivereAcademic Unit of Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.
Ana M ValdesAcademic Unit of Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.

Funding

Medical Research Council MR/W026813/1Medical Research Council MR/Y010175/1
6 · The paper itself

Abstract

We investigated changes in microbiome composition and abundance of antimicrobial resistance (AMR) genes post-antibiotic treatment in severe trauma patients. Shotgun sequencing revealed beta diversity (Bray-Curtis) differences between 16 hospitalized multiple rib fractures patients and 10 age- and sex-matched controls (

Indexed as

GenomicsMicrobiomeTrauma

Identifiers

PMID39286492
PMCPMC11403444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.