Evidence map›Paper›PMID 39286381›Full record

ArticleWorld journal of clinical cases2024

Periorbital purpura can be the only initial symptom of primary light chain amyloidosis: A case report.

Xiu-Feng Wang, Ting Li, Man Yang, Yan Huang

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical cases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiu-Feng WangDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan Province, China. 81848616@qq.com.
Ting LiDepartment of Blood Purification, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan Province, China.
Man YangDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan Province, China.
Yan HuangDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary light chain amyloidosis is a rare and complex disease with complex clinical features and is highly susceptible to misdiagnosis and underdiagnosis in the early stages. CASE SUMMARY: We report a case of a 47-year-old female patient whose only initial symptom was periorbital purpura, which was not taken seriously enough. As the disease progressed, pleural effusion gradually appeared, and after systematic diagnosis and treatment, she was diagnosed with "primary light chain amyloidosis". She achieved rapid hematological remission after treatment with a daratumumab + bortezomib + cyclophosphamide + dexamethasone regimen.

conclusionPeriorbital purpura can be the only initial symptom of primary light chain amyloidosis; we should pay attention to the cases where the initial clinical symptoms are only periorbital purpura.

Indexed as

Case reportInitial symptomLiterature reviewPeriorbital purpuraPrimary light chain amyloidosis

Identifiers

PMID39286381
PMCPMC11287502

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