Evidence map›Paper›PMID 39286328›Full record

ReviewNew microbes and new infections2024

Adverse pregnancy outcomes in maternal malarial infection: A systematic review and meta-analysis.

Prakasini Satapathy, Mahalaqua Nazli Khatib, Shilpa Gaidhane, Quazi Syed Zahiruddin, Rakesh Kumar Sharma, Sarvesh Rustagi, Jumana M Al-Jishi, Hawra Albayat, Mona A Al Fares, Mohammed Garout and 4 more

Abstract readReview
In one paragraph

Review in New microbes and new infections, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Prakasini SatapathyCenter for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Mahalaqua Nazli KhatibDivision of Evidence Synthesis, Global Consortium of Public Health and Research, Datta Meghe Institute of Higher Education, Wardha, India.
Shilpa GaidhaneOne Health Centre (COHERD), Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education, Wardha, India.
Quazi Syed ZahiruddinSouth Asia Infant Feeding Research Network (SAIFRN), Division of Evidence Synthesis, Global Consortium of Public Health and Research, Datta Meghe Institute of Higher Education, Wardha, India.
Rakesh Kumar SharmaGraphic Era (Deemed to Be University), Clement Town, Dehradun, India.
Sarvesh RustagiSchool of Applied and Life Sciences, Uttaranchal University, Dehradun, Uttarakhand, India.
Jumana M Al-JishiInternal Medicine Department, Qatif Central Hospital, Qatif, 32654, Saudi Arabia.
Hawra AlbayatInfectious Disease Department, King Saud Medical City, Riyadh, 7790, Saudi Arabia.
Mona A Al FaresDepartment of Internal Medicine, King Abdulaziz University Hospital, Jeddah, 21589, Saudi Arabia.
Mohammed GaroutDepartment of Community Medicine and Health Care for Pilgrims, Faculty of Medicine, Umm Al-Qura University, Makkah, 21955, Saudi Arabia.
Hayam A AlrasheedDepartment of Pharmacy Practice, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, 11671, Saudi Arabia.
Maha F Al-SubaieResearch Center, Dr. Sulaiman Alhabib Medical Group, Riyadh, 13328, Saudi Arabia.
Ali A RabaanResearch Center, Dr. Sulaiman Alhabib Medical Group, Riyadh, 13328, Saudi Arabia.
Ranjit SahTribhuvan University Teaching Hospital, Kathmandu, 46000, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Malaria in pregnancy is a critical public health issue that can lead to severe adverse outcomes for both mother and fetus. This systematic review and meta-analysis evaluated the prevalence of adverse birth outcomes in malaria-infected pregnancies and examines their association with the condition. Method: We searched databases up to January 30, 2024, for observational studies on pregnant women with malaria. Data were analyzed using a random-effects model to calculate pooled prevalence rates and risk ratios (RRs) for adverse outcomes, with statistical support from R software version 4.3. Results: Thirty-one studies were included, showing high prevalence of low birth weight (LBW; 17.4 %), preterm birth (17.9 %), and small for gestational age (SGA; 16.1 %) in malaria-affected pregnancies. Infected mothers were significantly more likely to have LBW infants (RR = 1.755), preterm births (RR = 1.484), and SGA infants (RR = 1.554). The risk of stillbirth was not significantly increased (RR = 1.238). Conclusion: Malaria in pregnancy significantly elevates the risk of LBW, preterm birth, and SGA, underscoring the need for effective malaria prevention and treatment strategies in endemic regions. Future research should aim to refine and implement these strategies to enhance maternal and neonatal health outcomes.

Indexed as

Low birthweightMalariaMeta-analysisPlasmodiumPreterm birthStillbirth

Identifiers

PMID39286328
PMCPMC11403273

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.