Evidence map›Paper›PMID 39286269›Full record

ArticleFrontiers in endocrinology2024

Paraventricular oxytocin neurons impact energy intake and expenditure: projections to the bed nucleus of the stria terminalis reduce sucrose consumption.

Amy A Worth, Claire H Feetham, Nicole A Morrissey, Simon M Luckman

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amy A WorthFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Claire H FeethamFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Nicole A MorrisseyFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Simon M LuckmanFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Funding

Medical Research Council MR/P024017/1
6 · The paper itself

Abstract

Background: The part played by oxytocin and oxytocin neurons in the regulation of food intake is controversial. There is much pharmacological data to support a role for oxytocin notably in regulating sugar consumption, however, several recent experiments have questioned the importance of oxytocin neurons themselves. Methods: Here we use a combination of histological and chemogenetic techniques to investigate the selective activation or inhibition of oxytocin neurons in the hypothalamic paraventricular nucleus (Oxt Results: Oxt Conclusion: Our results support a role for oxytocin neurons in the regulation of whole-body metabolism, including a modulatory action on food intake and energy expenditure. Furthermore, we demonstrate that the pathway from Oxt

Indexed as

Energy IntakeEnergy MetabolismNeuronsOxytocinParaventricular Hypothalamic NucleusSeptal NucleiAnimalsEatingMaleMiceMice, Inbred C57BLMice, TransgenicSucroseOxytocinSucroseBNSTchemogeneticfood intakeoptogeneticoxytocinparaventricular nucleussucrose

Identifiers

PMID39286269
PMCPMC11402739

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.