Evidence map›Paper›PMID 39286185›Full record

ArticleHeliyon2024

Computational investigation of novel synthetic analogs of C-1'β substituted remdesivir against RNA-dependent RNA-polymerase of SARS-CoV-2.

Savio Cardoza, Anirudh Singh, Souvik Sur, Mintu Singh, Kshatresh D Dubey, Sintu Kumar Samanta, Ajay Mandal, Vibha Tandon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Savio CardozaSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India.
Anirudh SinghDepartment of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, 211012, Uttar Pradesh, India.
Souvik SurResearch and Development Center, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, 240001, India.
Mintu SinghSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India.
Kshatresh D DubeyDepartment of Chemistry, Shiv Nadar University, Gautam Buddha Nagar, Uttar Pradesh, 201314, India.
Sintu Kumar SamantaDepartment of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, 211012, Uttar Pradesh, India.
Ajay MandalSymbol Discovery Ltd, ASPIRE-TBI, School of Life Sciences, University of Hyderabad, Gachibowli, Hyderabad, 500046, India.
Vibha TandonSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Remdesivir, a C-nucleotide prodrug binds to the viral RNA-dependent-RNA polymerase (

Indexed as

MD simulationsMolecular dockingRemdesivir analogs

Identifiers

PMID39286185
PMCPMC11402944

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.