ArticleResearch (Washington, D.C.)2022
Neuromodulation of Chemical Synaptic Transmission Driven by THz Photons.
Article in Research (Washington, D.C.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
17 citing papers in PubMed.
- Terahertz wave stimulation improves visual recognition memory via the activation of excitatory neurons in the perirhinal cortex.Cell communication and signaling : CCS · 2026Article
- Noninvasive Terahertz Wave Binocular Stimulation Improves Cognition in Amyloid-β-Related Dementia.Research (Washington, D.C.) · 2026Article
- Mid-infrared photons relieve tinnitus-like behavior of mice by regulating HCN2 ion channels in the medial geniculate body.Annals of medicine · 2025Article
- Spatiotemporal terahertz modulation enhances NMDAR-mediated miniature EPSCs.Scientific reports · 2025Article
- The Role of Glutamatergic Neurons in Changes of Synaptic Plasticity Induced by THz Waves.Biomolecules · 2025Article
- THz Waves Improve Spatial Working Memory by Increasing the Activity of Glutamatergic Neurons in Mice.Cells · 2025Article
- A new horizon for neuroscience: terahertz biotechnology in brain research.Neural regeneration research · 2025Article
- Study on the Effect of the Envelope of Terahertz Unipolar Stimulation on Cell Membrane Communication-Related Variables.Research (Washington, D.C.) · 2025Article
- Terahertz Science and Technology in Astronomy, Telecommunications, and Biophysics.Research (Washington, D.C.) · 2025Review
- Advances in Terahertz Biophysics and Chemistry.Research (Washington, D.C.) · 2025Review
- Progress of the Impact of Terahertz Radiation on Ion Channel Kinetics in Neuronal Cells.Neuroscience bulletin · 2024Review
- Terahertz Radiation Modulates Neuronal Morphology and Dynamics Properties.Brain sciences · 2024Review
- Terahertz Wave Alleviates Comorbidity Anxiety in Pain by Reducing the Binding Capacity of Nanostructured Glutamate Molecules to GluA2.Research (Washington, D.C.) · 2024Article
- Resonating with Cellular Pathways: Transcriptome Insights into Nonthermal Bioeffects of Middle Infrared Light Stimulation and Vibrational Strong Coupling on Cell Proliferation and Migration.Research (Washington, D.C.) · 2024Article
- Mid-Infrared Photons Alleviate Tinnitus by Activating the KCNQ2 Channel in the Auditory Cortex.Research (Washington, D.C.) · 2024Article
- Terahertz Photons Improve Cognitive Functions in Posttraumatic Stress Disorder.Research (Washington, D.C.) · 2023Article
- High-Efficiency Dynamic Terahertz Deflector Utilizing a Mechanically Tunable Metasurface.Research (Washington, D.C.) · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postsynaptic currents of chemical synapse are modulated by multitudinous neurotransmitters, such as acetylcholine, dopamine, glutamate, and γ-aminobutyric acid, many of which have been used in the treatment of neurological diseases. Here, based on molecular dynamics simulations and quantum chemical calculation, we propose that 30- to 45-THz photons can resonate with a variety of typical neurotransmitter molecules and make them absorb photon energy to activate the transition to high energy state, which is expected to be a new method of neural regulation. Furthermore, we verified the calculated results through experiments that THz irradiation could substantively change neuronal signal emission and enhance the frequency, amplitude, and dynamic properties of excitatory postsynaptic current and inhibitory postsynaptic current. In addition, we demonstrated the potential of neural information regulation by THz photons through 2-photon imaging in vivo. These findings are expected to improve the understanding of the physical mechanism of biological phenomena and facilitate the application of terahertz technology in neural regulation and the development of new functional materials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.