Evidence map›Paper›PMID 39285622›Full record

ArticleMagnetic resonance in medicine2025

Comparison of 3D UTE free-breathing lung MRI with hyperpolarized

Samal Munidasa, Brandon Zanette, Marie-Pier Dumas, Wallace Wee, Sharon Braganza, Daniel Li, Felix Ratjen, Giles Santyr

Abstract readComparative Study
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samal MunidasaTranslational Medicine Program, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0001-5948-6234
Brandon ZanetteTranslational Medicine Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Marie-Pier DumasDivision of Respiratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
Wallace WeeDivision of Respiratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
Sharon BraganzaTranslational Medicine Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Daniel LiTranslational Medicine Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Felix RatjenTranslational Medicine Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Giles SantyrTranslational Medicine Program, The Hospital for Sick Children, Toronto, Ontario, Canada.

Funding

Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada RGPIN 217015-2013CIHR MOP 123431CIHR PJT 153099Cystic Fibrosis Foundation
6 · The paper itself

Abstract

purposeTo compare phase-resolved functional lung (PREFUL) regional ventilation derived from a free breathing 3D UTE radial MRI acquisition to hyperpolarized

methodsFree-breathing 3D UTE and 2D multi-slice

resultsGlobal 3D VDP

conclusionAbsolute VDP assessed by 3D UTE PREFUL MRI showed good global agreement with Xe-MRI and 2D multi-slice PREFUL MRI in pediatric CF lung disease. Therefore, 3D UTE PREFUL MRI offers a sensitive and potentially more accessible alternative to Xe-MRI for regional volumetric evaluation of ventilation.

Indexed as

Cystic FibrosisImaging, Three-DimensionalLungMagnetic Resonance ImagingXenon IsotopesAdolescentChildFemaleHumansMaleReproducibility of ResultsRespirationRespiratory Function TestsXenon-129Xenon Isotopes3D free‐breathing 1‐H imagingcystic fibrosishyperpolarized 129Xenon imagingpulmonary ventilationultra‐short echo time

Identifiers

PMID39285622
PMCPMC11604841

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.