ArticleJournal of the Chinese Medical Association : JCMA2025
Comparison of clinical outcomes in women with surgically treated early primary cervical cancer: Lymphadenectomy vs sentinel lymph node biopsy.
Article in Journal of the Chinese Medical Association : JCMA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of Biomedical Materials for the Prevention of Lymphocele after Lymph Node Dissection for Gynecological Malignancies: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Gynecologic and obstetric investigation · 2026Pooled it
- The trend of utilizing de-escalation of surgical extent for treating early-stage cervical cancer patients.Journal of the Chinese Medical Association : JCMA · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe primary objective of this study was to elucidate the impact of sentinel lymph node (SLN) mapping and biopsy techniques on the clinical outcomes of women with early primary cervical cancer.
methodsAll consecutive women with clinically determined stage I-IIA cervical cancer who underwent lymph node assessment with either SLN mapping or conventional pelvic/para-aortic lymphadenectomy were reviewed.
resultsWomen in the SLN group (n = 33) had fewer total dissected pelvic nodes (8.3 ± 5.9 vs 17.4 ± 7.7, p < 0.001), less intraoperative blood loss (513 ± 332 vs 1228 ± 1170 mL, p < 0.001), a shorter length of hospital stay (7.1 ± 2.4 vs 10.2 ± 6.1 days, p = 0.004) than women in the conventional lymphadenectomy group (n = 74). The rates of recurrence-free survival (3-year: 87.6% vs 82.9%) and overall survival (3-year: 100% vs 91.0%) did not differ between the SLN group and the conventional lymphadenectomy group ( p = 0.846 and p = 0.254, respectively).
conclusionSLN biopsy does not seem to be associated with an inferior survival outcome compared with conventional lymphadenectomy in women with early primary cervical cancer. In addition, it is associated with less blood loss and a shorter length of hospital stay.
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