Evidence map›Paper›PMID 39285327›Full record

ArticleBMC medical imaging2024

Application research on the diagnosis of classic trigeminal neuralgia based on VB-Net technology and radiomics.

Lei Pan, Xuechun Wang, Xiuhong Ge, Haiqi Ye, Xiaofen Zhu, Qi Feng, Haibin Wang, Feng Shi, Zhongxiang Ding

Abstract read
In one paragraph

Article in BMC medical imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lei Pan *Department of Radiology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, 310000, Zhejiang, China.
Xuechun Wang *Department of Research and Development, Shanghai United Imaging Intelligence Co., Ltd, 701 Yunjin Road, Shanghai, 200030, China.
Xiuhong GeDepartment of Radiology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, 310000, Zhejiang, China.
Haiqi YeDepartment of Radiology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, 310000, Zhejiang, China.
Xiaofen ZhuDepartment of Radiology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, 310000, Zhejiang, China.
Qi FengDepartment of Radiology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, 310000, Zhejiang, China.
Haibin WangDepartment of Radiology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, 310000, Zhejiang, China.
Feng ShiDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd, 701 Yunjin Road, Shanghai, 200030, China. feng.shi@uii-ai.com.
Zhongxiang DingDepartment of Radiology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, 310000, Zhejiang, China. hangzhoudzx73@126.com.

Funding

Hangzhou Agriculture and Social Development Scientific Research Guidance Project 20211231Y022National Natural Science Foundation of China 81871337Zhejiang Medical and Health Research Project 2021RC102Zhejiang Provincial Medical and Health Technology Project 2024KY1313
6 · The paper itself

Abstract

backgroundThis study aims to utilize the deep learning method of VB-Net to locate and segment the trigeminal nerve, and employ radiomics methods to distinguish between CTN patients and healthy individuals.

methodsA total of 165 CTN patients and 175 healthy controls, matched for gender and age, were recruited. All subjects underwent magnetic resonance scans. VB-Net was used to locate and segment the bilateral trigeminal nerve of all subjects, followed by the application of radiomics methods for feature extraction, dimensionality reduction, feature selection, model construction, and model evaluation.

resultsOn the test set for trigeminal nerve segmentation, our segmentation parameters are as follows: the mean Dice Similarity Coefficient (mDCS) is 0.74, the Average Symmetric Surface Distance (ASSD) is 0.64 mm, and the Hausdorff Distance (HD) is 3.34 mm, which are within the acceptable range. Analysis of CTN patients and healthy controls identified 12 features with larger weights, and there was a statistically significant difference in Rad_score between the two groups (p < 0.05). The Area Under the Curve (AUC) values for the three models (Gradient Boosting Decision Tree, Gaussian Process, and Random Forest) are 0.90, 0.87, and 0.86, respectively. After testing with DeLong and McNemar methods, these three models all exhibit good performance in distinguishing CTN from normal individuals.

conclusionsRadiomics can aid in the clinical diagnosis of CTN, and it is a more objective approach. It serves as a reliable neurobiological indicator for the clinical diagnosis of CTN and the assessment of changes in the trigeminal nerve in patients with CTN.

Indexed as

Deep LearningMagnetic Resonance ImagingTrigeminal NeuralgiaAdultAgedCase-Control StudiesFemaleHumansMaleMiddle AgedRadiomicsTrigeminal NerveClassic trigeminal neuralgiaDeep learningNeuroimagingRadiomics

Identifiers

PMID39285327
PMCPMC11404009

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.