Evidence map›Paper›PMID 39285119›Full record

ArticleMolecular diversity2025

Design, synthesis, bioactivity and action mechanism of N-substituted N'-phenylpicolinohydrazides against phytopathogenic fungi.

Yuhao Zhang, Ruofei Bai, Tengyi Du, Yiwei Wang, Bohang Zhou, Congwei Zhou, Le Zhou

Abstract read
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In one paragraph

Article in Molecular diversity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuhao Zhang *College of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, Shaanxi, People's Republic of China.
Ruofei Bai *College of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, Shaanxi, People's Republic of China.
Tengyi DuCollege of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, Shaanxi, People's Republic of China.
Yiwei WangCollege of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, Shaanxi, People's Republic of China.
Bohang ZhouBio-Agriculture Institute of Shaanxi, Xi'an, 710043, Shaanxi, People's Republic of China.
Congwei ZhouCollege of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, Shaanxi, People's Republic of China.
Le ZhouCollege of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, Shaanxi, People's Republic of China. zhoulechem@nwsuaf.edu.cn.

Funding

National Natural Science Foundation of China No.31872008Science and Technology Program of Shaanxi Academy of Sciences-Seed Fund 2022K-19Shaanxi Province Key Research and Development Plan Program 2023-YBNY-240
6 · The paper itself

Abstract

N'-phenylpicolinohydrazide has been proven to be a promising lead compound for research and development of novel fungicides for agriculture in our previous study. As our continuing research, in this study, a series of N-substituted derivatives of N'-phenylpicolinohydrazide were synthesized and explored for the inhibition activity on nine phytopathogenic fungi and action mechanism. The results found that eleven of the compounds had excellent antifungal activity with more than 80% inhibition rates at 50 µg/mL on part or most of the fungi, especially A. solani and P. piricola. Compounds 5i, 5j and 5k showed EC

Indexed as

Antifungal AgentsDrug DesignFungiFungicides, IndustrialHydrazinesMicrobial Sensitivity TestsMolecular Docking SimulationPlant DiseasesSolanum lycopersicumStructure-Activity RelationshipAntifungal AgentsFungicides, IndustrialHydrazinesAntifungal activityFluorescent stainingMolecular dockingMycelial morphologyN'-phenylpicolinohydrazide

Identifiers

PMID39285119

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.