Evidence map›Paper›PMID 39285105›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2024

Development and evaluation of a loop-mediated isothermal amplification (LAMP) method for Candida glabrata detection.

H Yahaya, Y K Cheah, H Y Chee, L T L Than

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Nucleic Acid Amplification Tests forPathogens (Basel, Switzerland) · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

H YahayaDepartment of Medical Laboratory Science, Faculty of Allied Health Sciences, Bayero University, Kano, Nigeria.
Y K CheahDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, 43400, Selangor, Malaysia.
H Y CheeDepartment of Medical Microbiology, Universiti Putra Malaysia, Serdang, 43400, Selangor, Malaysia.
L T L ThanDepartment of Medical Microbiology, Universiti Putra Malaysia, Serdang, 43400, Selangor, Malaysia. leslie@upm.edu.my.

Funding

Fakulti Perubatan dan Sains Kesihatan, Universiti Putra Malaysia GP-IPS/2018/9612400
6 · The paper itself

Abstract

purposeLoop-mediated isothermal amplification (LAMP) is a simple and rapid nucleic acid method for DNA amplification at a constant temperature. The "gold standard" culture method for yeast detection, has low sensitivity with severe consequences, increasing morbidity and mortality rates. Here, we report the development of a LAMP method for the specific detection of C. glabrata. METHODOLOGY: The specific LAMP primers for C. glabrata detection were designed and evaluated.

resultsThe LAMP assay accurately detected C. glabrata with no cross-reactivity with other Candida species.

conclusionThe developed molecular method would be a promising tool in the management of invasive candidiasis.

Indexed as

Candida glabrataMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesSensitivity and SpecificityCandidiasisDNA, FungalDNA PrimersHumansDNA, FungalDNA PrimersC. glabrataCultureInvasive candidiasisLAMPPCR

Identifiers

PMID39285105

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.