ArticleInfection2025
Long/post-COVID in children and adolescents: symptom onset and recovery after one year based on healthcare records in Germany.
Article in Infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05074953 (Post-COVID-19 Monitoring in Routine Health Insurance Data), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Post-COVID-19 Monitoring in Routine Health Insurance Data
Who cites it
5 citing papers in PubMed.
- Mental and physical health differences between youth infected and uninfected by SARS-CoV-2: data from 2021 to 2023.Journal of pediatric psychology · 2026Observational
- Risk factors for severe post-COVID condition in children, adolescents, and young adults.European journal of pediatrics · 2026Observational
- Severe acute COVID-19 and early long COVID signals in paediatric cohorts: an analysis of real-world data from two health departments, Germany.BMC pediatrics · 2026Article
- Biomarkers of long COVID in children and young adults: a scoping review.European journal of pediatrics · 2026Article
- Improving Biomedical Science Literacy and Patient-Directed Knowledge of Tuberculosis (TB): A Cross-Sectional Infodemiology Study Examining Readability of Patient-Facing TB Information.British journal of biomedical science · 2024Article
Corrections and comments
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Authors and funding
24 authors.
Funding
Abstract
purposeEvidence on the incidence and persistence of post-acute sequelae of COVID-19 (PASC) among children and adolescents is still limited.
methodsIn this retrospective cohort study, 59,339 children and adolescents with laboratory-confirmed COVID-19 in 2020 and 170,940 matched controls were followed until 2021-09-30 using German routine healthcare data. Incidence rate differences (ΔIR) and ratios (IRR) of 96 potential PASC were estimated using Poisson regression. Analyses were stratified according to age (0-11, 12-17 years), and sex. At the individual level, persistence of diagnoses in patients with onset symptoms was tracked starting from the first quarter post-infection.
resultsAt 0-3 month follow-up, children and adolescents with a previous SARS-CoV-2 infection showed a 34% increased risk of adverse health outcome, and approximately 6% suffered from PASC in association with COVID-19. The attributable risk was higher among adolescents (≥ 12 years) than among children. For most common symptoms, IRRs largely persisted at 9-12 month follow-up. IRR were highest for rare conditions strongly associated with COVID-19, particularly inflammatory conditions among children 0-11 years, and chronic fatigue and respiratory insufficiency among adolescents. Tracking of diagnoses at the individual level revealed similar rates in the decline of symptoms among COVID-19 and control cohorts, generally leaving less than 10% of the patients with persistent diagnoses after 12 months.
conclusionAlthough very few patients presented symptoms for longer than 12 months, excess morbidity among children and, particularly, adolescents with a history of COVID-19 means a relevant burden for pediatric care.
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