Evidence map›Paper›PMID 39284902›Full record

ArticleScientific reports2024

Mentha arvensis oil exhibits repellent acute toxic and antioxidant activities in Nauphoeta cinerea.

Carlos Alonso Leite Dos Santos, Amanda Maria Tavares Moreira, Bárbara Rayanne da Silva Teles, Jean Paul Kamdem, Abdullah F AlAsmari, Fawaz Alasmari, Momin Khan, Luiz Marivando Barros, Mohammad Ibrahim

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Toxicology research · 2026
    Article
  2. Article
  3. Repellent efficacy of water-balm formulation againstCurrent research in parasitology & vector-borne diseases · 2026
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Carlos Alonso Leite Dos SantosLaboratory of Biology and Toxicology, Regional University of Cariri (URCA), Crato, CE, Brazil.
Amanda Maria Tavares MoreiraLaboratory of Plant Ecophysiology, Regional University of Cariri (URCA), Crato, CE, Brazil.
Bárbara Rayanne da Silva TelesLaboratory of Entomology, Federal University of Cariri (UFCA), Crato, CE, Brazil.
Jean Paul KamdemDepartment of Biochemistry, Microbiology and Immunology (BMI), College of Medicine, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK, S7N 5E5, Canada.
Abdullah F AlAsmariDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Fawaz AlasmariDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Momin KhanDepartment of Chemistry, Abdul Wali Khan University Mardan (AWKUM) KPK, Mardan, 23200, Pakistan.
Luiz Marivando BarrosLaboratory of Plant Ecophysiology, Regional University of Cariri (URCA), Crato, CE, Brazil.
Mohammad IbrahimDepartment of Chemistry, Abdul Wali Khan University Mardan (AWKUM) KPK, Mardan, 23200, Pakistan. dribrahim@awkum.edu.pk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mentha arvensis is an herbaceous plant commonly known as peppermint or Japanese mint. This study investigated the toxic potential and repellent efficacy of M. arvensis essential oil (MaEO) at varying concentrations (15.625-250 mg/mL) in Nauphoeta cinerea, along with its impact on biochemical parameters in N. cinerea. The potential of the major compounds as a new analgesic target was investigated using molecular docking. The essential oil was analyzed by gas Chromatography-mass spectrometry (GC-MS) and the toxic potential, repellent property, and changes in lipid peroxidation (LPO) levels were evaluated as markers of oxidative stress. GC-MS results revealed that the main components were oxygenated monoterpenes such as menthol (71.31%), mentone (13.34%) and isomentone (5.35%). MaEO significantly reduced lipid peroxidation (LPO), the levels of non-protein thiols and iron(II) at the concentration of 125 mg/mL in N. cinerea. Furthermore, the major components, L-(-)-Menthol and menthone demonstrated high gastrointestinal absorption and high affinity with the target protein, suggesting possible links that contribute to the analgesic effect of MaEO.

Indexed as

AntioxidantsLipid PeroxidationMenthaOils, VolatileAnimalsGas Chromatography-Mass SpectrometryInsect RepellentsMolecular Docking SimulationOxidative StressPlant OilsAntioxidantsInsect RepellentsOils, VolatilePlant OilsEssential oilMentha arvensisOxidative stressPhytochemical prospectingToxicity

Identifiers

PMID39284902
PMCPMC11405674

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.