ArticleScientific reports2024
Isolation, characterization and antimicrobial activity study of Thymus vulgaris.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Thymol Chemotype Thymus vulgaris L. Hydrolate: Volatile Chemical Fraction Composition and Antimicrobial Activity Against Bacterial and Fungal Pathogens.Chemistry & biodiversity · 2026Article
- Antibacterial and Antibiofilm Potential of Thymol-Benzimidazolium-Chalcone Hybrids Against Clinical MRSA Strains: Insights from Gene Expression Profiling and Molecular Docking.Antibiotics (Basel, Switzerland) · 2026Article
- Electrospun Poly(vinylpyrrolidone)/Materials (Basel, Switzerland) · 2026Article
- Comparative Evaluation of Pesticidal Potential of Five Aromatic Plants, with Emphasis on the Fungicidal Activity ofMicroorganisms · 2026Article
- Biocompatible and Antimicrobial Cellulosic Support via Bioactive Emulsion-Based Film.Polymers · 2026Article
- Thyme Essential Oil Nanoemulsion Stabilized by Chitosan Nanoparticles for Potential Application in Food Preservation.Polymers · 2026Article
- Mechanistic evaluation of the in vitro antiviral and anti-inflammatory potential of thyme and licorice herbal preparation.Scientific reports · 2026Article
- Dietary polyphenols and human health: sources, biological activities, nutritional and immunological aspects, and bioavailability- a comprehensive review.Frontiers in immunology · 2025Review
- Herbal medicine approach to relieving dyspnea: A narrative review of efficacy and mechanisms.Iranian journal of basic medical sciences · 2025Review
- Article
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Authors and funding
6 authors.
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Abstract
Herbal medicines are important for ensuring sustainable development goals (SDGs) in healthcare, particularly in developing countries with high rates of antimicrobial resistance (AMR) and little access to medical facilities. Thymus vulgaris is a widely used herbal medicinal plant known for its secondary metabolites and antimicrobial properties. The present study involved a comprehensive examination of the isolation, characterization, and antibacterial activity of Thymus vulgaris obtained from Ethiopia. The aerial part of the plant Thymus vulgaris was successively extracted with hexane, chloroform, and methanol based on differences in polarity. Phytochemical screening tests conducted against hexane, chloroform and MeOH crude extracts indicated the presence of some secondary metabolites. Based on the thin-layer chromatography tests, the chloroform extract was subjected to column chromatography, yielding Tv-2 compounds, namely 5-isopropyl-2-methylphenol. The structures of the compounds were elucidated via spectroscopic methods (UV-Vis, FT-IR and NMR). We investigated the antibacterial properties of hexane crude extract, chloroform crude extract, MeOH crude extract, and isolated fractions derived from T. vulgaris against various bacterial strains. This study contributes to a better understanding of the bioactive components present in Thymus vulgaris crude extracts and their potential role in tackling microbial infections.
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