Evidence map›Paper›PMID 39284859›Full record

ArticleCommunications biology2024

An intranasal cationic liposomal polysaccharide vaccine elicits humoral immune responses against Streptococcus pneumoniae.

Peng Wei, Cecilia Romanò, Chengxin Li, Gael Clergeaud, Thomas L Andresen, Jonas R Henriksen, Anders E Hansen, Mads H Clausen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peng WeiCenter for Nanomedicine and Theranostics, Department of Chemistry, Technical University of Denmark, Kongens Lyngby, 2800, Denmark.ORCID 0000-0002-7254-1856
Cecilia RomanòCenter for Nanomedicine and Theranostics, Department of Chemistry, Technical University of Denmark, Kongens Lyngby, 2800, Denmark.
Chengxin LiDepartment of Chemistry, Technical University of Denmark, Kongens Lyngby, 2800, Denmark.
Gael ClergeaudSection for Biotherapeutic Engineering and Drug Targeting, Department of Health Technology, Technical University of Denmark, Kongens Lyngby, 2800, Denmark.
Thomas L AndresenSection for Biotherapeutic Engineering and Drug Targeting, Department of Health Technology, Technical University of Denmark, Kongens Lyngby, 2800, Denmark.ORCID 0000-0002-1048-127X
Jonas R HenriksenSection for Biotherapeutic Engineering and Drug Targeting, Department of Health Technology, Technical University of Denmark, Kongens Lyngby, 2800, Denmark.
Anders E HansenSection for Biotherapeutic Engineering and Drug Targeting, Department of Health Technology, Technical University of Denmark, Kongens Lyngby, 2800, Denmark.
Mads H ClausenCenter for Nanomedicine and Theranostics, Department of Chemistry, Technical University of Denmark, Kongens Lyngby, 2800, Denmark. mhc@kemi.dtu.dk.ORCID 0000-0001-9649-1729

Funding

Carlsbergfondet (Carlsberg Foundation) CF19-0072Carlsbergfondet (Carlsberg Foundation) CF22-1105Lundbeckfonden (Lundbeck Foundation) R347-2020-2307Novo Nordisk Fonden (Novo Nordisk Foundation) NNF18OC0053048Novo Nordisk Fonden (Novo Nordisk Foundation) NNF19OC0055818Novo Nordisk Fonden (Novo Nordisk Foundation) NNF20OC0065094),Teknologi og Produktion, Det Frie Forskningsråd (Technology and Production, Danish Council for Independent Research) 9041-00080B
6 · The paper itself

Abstract

Diseases caused by S. pneumoniae are the leading cause of child mortality. As antibiotic resistance of S. pneumoniae is rising, vaccination remains the most recommended solution. However, the existing pneumococcal polysaccharides vaccine (Pneumovax

Indexed as

Administration, IntranasalImmunity, HumoralLiposomesMice, Inbred BALB CPneumococcal InfectionsPneumococcal VaccinesStreptococcus pneumoniaeAnimalsAntibodies, BacterialCationsFemaleMicePolysaccharides, BacterialAntibodies, BacterialCationsLiposomesPneumococcal VaccinesPolysaccharides, Bacterial

Identifiers

PMID39284859
PMCPMC11405767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.