Evidence map›Paper›PMID 39283579›Full record

Trial reportAnnals of surgical oncology2024

Inspiratory Muscle Training Before Esophagectomy Increases Diaphragmatic Excursion: A Randomized Controlled Trial.

Hiroki Mizusawa, Yuji Higashimoto, Osamu Shiraishi, Masashi Shiraishi, Ryuji Sugiya, Masaya Noguchi, Shuhei Fujita, Tamotsu Kimura, Akira Ishikawa, Takushi Yasuda

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Annals of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroki MizusawaDepartment of Rehabilitation Medicine, Faculty of Medicine, Kindai University, Osakasayama-City, Osaka, Japan. hiroki-mizusawa@med.kindai.ac.jp.ORCID http://orcid.org/0000-0001-8324-4294
Yuji HigashimotoDepartment of Rehabilitation Medicine, Faculty of Medicine, Kindai University, Osakasayama-City, Osaka, Japan.
Osamu ShiraishiDepartment of Surgery, Faculty of Medicine, Kindai University, Osaka, Japan.
Masashi ShiraishiDepartment of Rehabilitation Medicine, Faculty of Medicine, Kindai University, Osakasayama-City, Osaka, Japan.
Ryuji SugiyaDepartment of Rehabilitation Medicine, Faculty of Medicine, Kindai University, Osakasayama-City, Osaka, Japan.
Masaya NoguchiDepartment of Rehabilitation Medicine, Faculty of Medicine, Kindai University, Osakasayama-City, Osaka, Japan.
Shuhei FujitaDepartment of Rehabilitation Medicine, Faculty of Medicine, Kindai University, Osakasayama-City, Osaka, Japan.
Tamotsu KimuraDepartment of Rehabilitation Medicine, Faculty of Medicine, Kindai University, Osakasayama-City, Osaka, Japan.
Akira IshikawaDepartment of Public Health, Graduate School of Health Sciences, Kobe University, Kobe, Japan.
Takushi YasudaDepartment of Surgery, Faculty of Medicine, Kindai University, Osaka, Japan.

Funding

Grant-In-Aid for Scientific Research from the Ministry of Education, Science and Culture of the Japanese Government 24K20485
6 · The paper itself

Abstract

backgroundInspiratory muscle training (IMT) has preventive effects against postoperative pulmonary complications (PPCs) after upper abdominal surgery. However, its impact on diaphragmatic function has not been evaluated. This study investigated the effect of preoperative IMT on diaphragmatic excursion (DE) and prevention of PPCs for patients with esophageal cancer.

methodsThis study was an unblinded, parallel, randomized controlled trial. Patients with thoracic or abdominal esophageal cancer scheduled for esophagectomy were randomized into the incentive spirometry (IS) or IMT group. During preoperative neoadjuvant chemotherapy, IS or IMT intervention was performed. The inspiratory resistance of the IMT group was consistently set at 50% maximal inspiratory pressure. The primary outcome was the amount of change in DE evaluated with ultrasonography, and the secondary outcome was the incidence of Clavien-Dindo grade II or higher PPCs.

resultsThis study recruited 42 patients. Among these patients 21 were randomized into the IS or IMT group, and 2 patients dropped out from the study. Finally, 40 patients were included in this analysis. The DE of the IMT group increased significantly after the intervention. The IMT group had significantly larger DE changes than the IS group. Of the 39 patients analyzed for postoperative outcome, 5 experienced grade II PPCs. The IMT group had a lower incidence of PPCs than the IS group.

conclusionsPatients with thoracic and abdominal esophageal cancer scheduled for surgery who had preoperative IMT have increased DE, which may have an important role in prevention of PPCs.

Indexed as

Breathing ExercisesDiaphragmEsophageal NeoplasmsEsophagectomyPostoperative ComplicationsAgedFemaleFollow-Up StudiesHumansInhalationMaleMiddle AgedPrognosisRespiratory MusclesDiaphragmatic excursionEsophagectomyInspiratory muscle trainingPostoperative pulmonary complicationsUltrasonography

Identifiers

PMID39283579

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.