Evidence map›Paper›PMID 39283538›Full record

ArticleSpine deformity2025

Optimizing sacral screw fixation in patients with caudal regression syndrome.

Olga M Sergeenko, Dmitry M Savin, Anastacia Gabrielyan, Yulia S Arestova, Sergey O Ryabykh, Alexander V Burtsev, Alexey V Evsyukov

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Article in Spine deformity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Olga M SergeenkoDivision of Spinal Surgery, Ilizarov Center, Kurgan, Russia. pavlova.neuro@mail.ru.ORCID http://orcid.org/0000-0003-2905-0215
Dmitry M SavinDivision of Spinal Surgery, Ilizarov Center, Kurgan, Russia.ORCID http://orcid.org/0000-0002-4395-2103
Anastacia GabrielyanDivision of Spinal Surgery, Ilizarov Center, Kurgan, Russia.ORCID http://orcid.org/0009-0008-1527-6452
Yulia S ArestovaDivision of Spinal Surgery, Ilizarov Center, Kurgan, Russia.ORCID http://orcid.org/0000-0003-1169-9753
Sergey O RyabykhPirogov's Russian National Medical University, Moscow, Russia.ORCID http://orcid.org/0000-0002-8293-0521
Alexander V BurtsevDivision of Spinal Surgery, Ilizarov Center, Kurgan, Russia.ORCID http://orcid.org/0000-0001-8968-6528
Alexey V EvsyukovDivision of Spinal Surgery, Ilizarov Center, Kurgan, Russia.ORCID http://orcid.org/0000-0001-8583-0270

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to evaluate and compare techniques and outcomes associated with two different technique of pelvic screw insertion in patients with caudal spine absence.

methodsA cohort of patients with varying degrees of caudal structural regression, serves as the focal point of this investigation. Pelvic configurations were classified based on established criteria to facilitate comparative analysis. Each patient underwent spinal surgical interventions, with a follow-up period extending beyond 2 years. The primary surgical interventions predominantly involved spinal stabilization coupled with correction of scoliosis and kyphosis through one or two pairs of pelvic screws.

resultsIn this study, we investigated a cohort of 22 patients with caudal spine absence, encompassing diverse conditions, such as lumbo-sacral aplasia, hemisacrum, and lumbar absence, with preserved sacrum. Following spinal surgery, notable improvements were observed in scoliosis and pathological lumbar kyphosis, with several patients achieving significant functional milestones such as independent ambulation. There were no significant differences in short-term complications between patients undergoing single versus double pair pelvic screw implantation. Long-term complications, primarily non-fusion, were notably more prevalent in patients undergoing fixation with a single pair of pelvic screws.

conclusionSurgical intervention, particularly spinopelvic fixation, demonstrated promising outcomes in terms of improving spinal deformities. The implantation of two pairs of pelvic screws demonstrates greater reliability compared to the insertion of a single pair, diminishing the risk of non-fusion.

Indexed as

Bone ScrewsSacrumScoliosisSpinal FusionAdolescentAdultChildFemaleHumansKyphosisLumbar VertebraeMalePelvic BonesTreatment OutcomeYoung AdultCaudal regressionLumbo-sacral agenesisLumbo-sacral aplasiaSacral agenesisSacral aplasiaSegmental spinal dysgenesis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.