Evidence map›Paper›PMID 39282885›Full record

ArticleVirulence2024

Adaptations to cationic biocide exposure differentially influence virulence factors and pathogenicity in

Germán G Vargas-Cuebas, Christian A Sanchez, Elise L Bezold, Gabrielle M Walker, Shehreen Siddiqui, Kevin P C Minbiole, William M Wuest

Abstract read
In one paragraph

Article in Virulence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Germán G Vargas-CuebasDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Christian A SanchezDepartment of Chemistry, Emory University, Atlanta, GA, USA.
Elise L BezoldDepartment of Chemistry, Emory University, Atlanta, GA, USA.
Gabrielle M WalkerDepartment of Chemistry, Emory University, Atlanta, GA, USA.
Shehreen SiddiquiDepartment of Chemistry, Emory University, Atlanta, GA, USA.
Kevin P C MinbioleDepartment of Chemistry, Villanova University, Villanova, PA, USA.ORCID 0000-0003-4263-9833
William M WuestDepartment of Chemistry, Emory University, Atlanta, GA, USA.ORCID 0000-0002-5198-7744

Funding

Graduate Training in the Pharmacological StudiesT32GM008602 · NIGMS · EMORY UNIVERSITY · PI HALL, RANDY A. · 1996 to 2021
$5.1M
Natural Product-Inspired Approaches Toward The Development Of Antivirulence And Species-Specific InhibitorsR35GM119426 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI William M Wuest · 2016 to 2026
$4.8M
Investigating the impact of collagenase in Clostridioides difficile pathogenesisF31DK126467 · NIDDK · EMORY UNIVERSITY · PI VARGAS-CUEBAS, GERMAN GABRIEL · 2020 to 2024
$141k
NIDDK NIH HHS DK126467NIDDK NIH HHS F31 DK126467NIGMS NIH HHS GM008602NIGMS NIH HHS R35 GM119426NIGMS NIH HHS T32 GM008602
6 · The paper itself

Abstract

Cationic biocides (CBs), which include quaternary ammonium compounds (QACs), are employed to mitigate the spread of infectious bacteria, but resistance to such surface disinfectants is rising. CB exposure can have profound phenotypic implications that extend beyond allowing microorganisms to persist on surfaces.

Indexed as

DisinfectantsPseudomonas aeruginosaPseudomonas InfectionsVirulence FactorsAdaptation, PhysiologicalAnimalsBenzalkonium CompoundsBiofilmsCationsDrug Resistance, BacterialMiceQuaternary Ammonium CompoundsVirulenceBenzalkonium CompoundsCationsDisinfectantsQuaternary Ammonium CompoundsVirulence Factorsantimicrobial resistancecross-resistanceDisinfectantPseudomonas aeruginosavirulence factors

Identifiers

PMID39282885
PMCPMC11407422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.