Evidence map›Paper›PMID 39282592›Full record

ArticleJournal of clinical and experimental hepatology

Central Obesity is an Independent Determinant of Advanced Fibrosis in Lean Patients With Nonalcoholic Fatty Liver Disease.

Arka De, Naveen Bhagat, Manu Mehta, Priya Singh, Sahaj Rathi, Nipun Verma, Sunil Taneja, Madhumita Premkumar, Ajay Duseja

Abstract read
In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Arka DeDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Naveen BhagatDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Manu MehtaDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Priya SinghDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Sahaj RathiDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Nipun VermaDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Sunil TanejaDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Madhumita PremkumarDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ajay DusejaDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The current definition of lean is based on body mass index (BMI). However, BMI is an imperfect surrogate for adiposity and provides no information on central obesity (CO). Hence, we explored the differences in clinical profile and liver disease severity in lean patients with nonalcoholic fatty liver disease (NAFLD) with and without CO. Methods: One hundred seventy lean patients with NAFLD (BMI <23 kg/m Results: Of 170 patients with lean NAFLD, 96 (56.5%) had CO. Female gender (40.6% vs. 17.6%, Conclusion: Lean patients with NAFLD or MASLD and CO have more severe liver disease compared to those without CO.

Indexed as

BMIMAFLDMASLDNASHwaist circumference

Identifiers

PMID39282592
PMCPMC11399567

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.