Evidence map›Paper›PMID 39282449›Full record

ArticlebioRxiv : the preprint server for biology2024

Immune targets for schistosomiasis control identified by a genome-wide association study of East African snail vectors.

Tom Pennance, Jacob A Tennessen, Johannie M Spaan, Tammie McQuistan, George Ogara, Fredrick Rawago, Kennedy Andiego, Boaz Mulonga, Meredith Odhiambo, Martin W Mutuku and 4 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Tom PennanceCollege of Osteopathic Medicine of the Pacific - Northwest, Western University of Health Sciences, Lebanon, OR, USA.ORCID 0000-0003-4898-462X
Jacob A TennessenHarvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-5015-4740
Johannie M SpaanCollege of Osteopathic Medicine of the Pacific - Northwest, Western University of Health Sciences, Lebanon, OR, USA.ORCID 0000-0002-2528-3583
Tammie McQuistanCollege of Osteopathic Medicine of the Pacific - Northwest, Western University of Health Sciences, Lebanon, OR, USA.
George OgaraCentre for Global Health Research, Kenya Medical Research Institute (KEMRI), P. O. Box 1578-40100, Kisumu, Kenya.
Fredrick RawagoCentre for Global Health Research, Kenya Medical Research Institute (KEMRI), P. O. Box 1578-40100, Kisumu, Kenya.
Kennedy AndiegoCentre for Global Health Research, Kenya Medical Research Institute (KEMRI), P. O. Box 1578-40100, Kisumu, Kenya.
Boaz MulongaCentre for Global Health Research, Kenya Medical Research Institute (KEMRI), P. O. Box 1578-40100, Kisumu, Kenya.
Meredith OdhiamboCentre for Global Health Research, Kenya Medical Research Institute (KEMRI), P. O. Box 1578-40100, Kisumu, Kenya.
Martin W MutukuCentre for Biotechnology Research and Development, Kenya Medical Research Institute (KEMRI), P.O. Box 54840-00200, Nairobi, Kenya.
Gerald M MkojiCentre for Biotechnology Research and Development, Kenya Medical Research Institute (KEMRI), P.O. Box 54840-00200, Nairobi, Kenya.ORCID 0000-0003-3417-1644
Eric S LokerDepartment of Biology, Center for Evolutionary and Theoretical Immunology, Parasite Division Museum of Southwestern Biology, University of New Mexico, Albuquerque, New Mexico, USA.ORCID 0000-0002-2916-9868
Maurice R OdiereCentre for Global Health Research, Kenya Medical Research Institute (KEMRI), P. O. Box 1578-40100, Kisumu, Kenya.ORCID 0000-0001-7561-4873
Michelle L SteinauerCollege of Osteopathic Medicine of the Pacific - Northwest, Western University of Health Sciences, Lebanon, OR, USA.ORCID 0000-0002-3745-2401

Funding

Snail-Related Studies of Transmission & Control of Schistosomiasis in KenyaR37AI101438 · NIAID · UNIVERSITY OF NEW MEXICO · PI ERIC SAMUEL LOKER · 2017 to 2026
$3.7M
Identifying schistosomiasis resistance genes of snail vectors in hotspot transmission zones: Translating from laboratory models to the field.R01AI141862 · NIAID · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI STEINAUER, MICHELLE L. · 2019 to 2023
$1.7M
NIAID NIH HHS R01 AI141862NIAID NIH HHS R37 AI101438
6 · The paper itself

Abstract

Schistosomiasis, afflicting >260 million people worldwide, could be controlled by preventing infection of freshwater snail vectors. Intestinal schistosomiasis, caused by

Indexed as

amplicon panelBiomphalariaGWASpathogen resistanceSchistosoma

Identifiers

PMID39282449
PMCPMC11398393

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.