Evidence map›Paper›PMID 39282362›Full record

ArticlebioRxiv : the preprint server for biology2024

Electrospun Fiber Surface Roughness Modulates Human Monocyte-Derived Macrophage Phenotype.

Aidan Alemifar, KaLia Burnette, Bryan Jandres, Samuel Hurt, Hubert M Tse, Jennifer L Robinson

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aidan AlemifarDepartment of Orthopaedic Surgery and Sports Medicine, University of Washington.ORCID 0000-0002-2562-3680
KaLia BurnetteDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center.
Bryan JandresDepartment of Biochemistry, University of Washington.
Samuel HurtDepartment of Chemical and Petroleum Engineering, University of Kansas.
Hubert M TseDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center.
Jennifer L RobinsonDepartment of Orthopaedic Surgery and Sports Medicine, University of Washington.

Funding

Determining the mechanism of IFIH1 disease-associated variants on beta-cell and immune responses in Type 1 diabetesR01DK127497 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI MATHEWS, CLAYTON E, MILLMAN, JEFFREY ROBERT · 2020 to 2023
$4.7M
Islet encapsulation to elicit localized immunosuppression and immune modulation following transplantationR01DK131716 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Eugenia Kharlampieva, HUBERT M TSE · 2023 to 2026
$2.9M
Beta-cell responses to oxidative stress and Type 1 diabetesR01DK126456 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI HUNTER, CHAD S, TSE, HUBERT M · 2021 to 2025
$2.3M
Beta-cell responses to oxidative stress and Type 1 diabetesR56DK126456 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HUNTER, CHAD S, TSE, HUBERT M · 2020 to 2020
$149k
NIDDK NIH HHS R01 DK126456NIDDK NIH HHS R01 DK127497NIDDK NIH HHS R01 DK131716NIDDK NIH HHS R56 DK126456
6 · The paper itself

Abstract

Injuries to fibrous connective tissues have very little capacity for self-renewal and exhibit poor healing after injury. Phenotypic shifts in macrophages play a vital role in mediating the healing response, creating an opportunity to design immunomodulatory biomaterials which control macrophage polarization and promote regeneration. In this study, electrospun poly(-caprolactone) fibers with increasing surface roughness (SR) were produced by increasing relative humidity and inducing vapor-induced phase separation during the electrospinning process. The impact of surface roughness on macrophage phenotype was assessed using human monocyte-derived macrophages

Identifiers

PMID39282362
PMCPMC11398424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.