Evidence map›Paper›PMID 39282277›Full record

ArticlebioRxiv : the preprint server for biology2024

The proteomic landscape and temporal dynamics of mammalian gastruloid development.

Riddhiman K Garge, Valerie Lynch, Rose Fields, Silvia Casadei, Sabrina Best, Jeremy Stone, Matthew Snyder, Chris D McGann, Jay Shendure, Lea M Starita and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Riddhiman K GargeDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-6774-0172
Valerie LynchDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.
Rose FieldsDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.
Silvia CasadeiDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0003-2619-5662
Sabrina BestBrotman Baty Institute for Precision Medicine, Seattle, Washington, USA.ORCID 0009-0008-6352-0106
Jeremy StoneBrotman Baty Institute for Precision Medicine, Seattle, Washington, USA.
Matthew SnyderBrotman Baty Institute for Precision Medicine, Seattle, Washington, USA.ORCID 0000-0001-7433-4343
Chris D McGannDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.
Jay ShendureDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-1516-1865
Lea M StaritaDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0003-2870-5099
Nobuhiko HamazakiDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-9228-233X
Devin K SchweppeDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-3241-6276

Funding

Technology to understand genetic variant effects in contextRM1HG010461 · NHGRI · UNIVERSITY OF WASHINGTON · PI Douglas M Fowler, Bruce Colston Trapnell · 2019 to 2026
$18.9M
Technology for evaluating drug-binding responses to small-molecule perturbationR35GM150919 · NIGMS · UNIVERSITY OF WASHINGTON · PI Devin Karl Schweppe · 2023 to 2026
$1.6M
NHGRI NIH HHS RM1 HG010461NIGMS NIH HHS R35 GM150919
6 · The paper itself

Abstract

Gastrulation is the highly coordinated process by which the early embryo breaks symmetry, establishes germ layers and a body plan, and sets the stage for organogenesis. As early mammalian development is challenging to study

Identifiers

PMID39282277
PMCPMC11398484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.