ArticlebioRxiv : the preprint server for biology2025
Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial cell state.
C Chiasson-MacKenzie, Y Zhang, E O'Loughlin, P S Dave, A S Menon, A D Westerfield, V Kumar, S N Bhatia, E Rheinbay, N Bardeesy and 2 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
C Chiasson-MacKenzieKrantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.ORCID 0000-0002-4820-9765 Y ZhangKrantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.
E O'LoughlinKrantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.ORCID 0000-0001-5940-6150 P S DaveKrantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.
A S MenonKrantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.
A D WesterfieldInstitute of Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
V KumarDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
S N BhatiaInstitute of Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
E RheinbayKrantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.ORCID 0000-0002-5566-6729 N BardeesyKrantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.
S L StottKrantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.ORCID 0000-0002-0349-0522 A I McClatcheyKrantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.ORCID 0000-0002-6150-3619 Funding
Synthetic vascularization and regeneration in engineered tissuesR01EB033821 · NIBIB · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI SANGEETA N. BHATIA, CHRISTOPHER S CHEN · 2023 to 2026
$2.2MInside-out construction of the biliary systemR01DK127177 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI MCCLATCHEY, ANDREA I · 2021 to 2024
$1.5MPrecision imaging of the spatial regulators of the hybrid epithelial/mesenchymal state in head and neck cancerR01DE033741 · NIDCR · MASSACHUSETTS GENERAL HOSPITAL · PI STOTT, SHANNON L · 2024 to 2024
$702kNIBIB NIH HHS R01 EB033821NIDCR NIH HHS R01 DE033741NIDDK NIH HHS R01 DK127177
6 · The paper itselfAbstract
Epithelial cancers disrupt tissue architecture and are often driven by mutations in genes that play important roles in normal epithelial morphogenesis. The intrahepatic biliary system is an epithelial tubular network that forms within the developing liver via the
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PMID39282270
PMCPMC11398422
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