Evidence map›Paper›PMID 39282121›Full record

ReviewPeerJ2024

Relationship between ferroptosis and mitophagy in acute lung injury: a mini-review.

Yunhua Cheng, Liling Zhu, Shuangxiong Xie, Binyuan Lu, Xiaoyu Du, Guanjiang Ding, Yan Wang, Linchong Ma, Qingxin Li

Abstract readReview
In one paragraph

Review in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yunhua Cheng *The First School of Clinical Medicine of Gansu University of Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu Province, China.
Liling Zhu *Department of Anesthesiology, Hunan Children's Hospital, Changsha, Hunan Province, China.
Shuangxiong XieThe First School of Clinical Medicine of Gansu University of Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu Province, China.
Binyuan LuThe First School of Clinical Medicine of Gansu University of Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu Province, China.
Xiaoyu DuMedical College of Northwest Minzu University, Northwest Minzu University, Lanzhou, Gansu Province, China.
Guanjiang DingThe First School of Clinical Medicine of Gansu University of Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu Province, China.
Yan WangThe First School of Clinical Medicine of Gansu University of Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu Province, China.
Linchong MaDepartment of Thoracic Surgery, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou, Gansu Province, China.
Qingxin LiDepartment of Thoracic Surgery, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou, Gansu Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lung injury (ALI) is one of the most deadly and prevalent diseases in the intensive care unit. Ferroptosis and mitophagy are pathological mechanisms of ALI. Ferroptosis aggravates ALI, whereas mitophagy regulates ALI. Ferroptosis and mitophagy are both closely related to reactive oxygen species (ROS). Mitophagy can regulate ferroptosis, but the specific relationship between ferroptosis and mitophagy is still unclear. This study summarizes previous research findings on ferroptosis and mitophagy, revealing their involvement in ALI. Examining the functions of mTOR and NLPR3 helps clarify the connection between ferroptosis and mitophagy in ALI, with the goal of establishing a theoretical foundation for potential therapeutic approaches in the future management of ALI.

Indexed as

Acute Lung InjuryFerroptosisMitophagyReactive Oxygen SpeciesAnimalsHumansTOR Serine-Threonine KinasesReactive Oxygen SpeciesTOR Serine-Threonine KinasesAcute lung injuryFerroptosisMechanismMitochondriaMitophagyRelationship

Identifiers

PMID39282121
PMCPMC11397134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.