Evidence map›Paper›PMID 39281866›Full record

ArticleResearch square2024

Proapoptotic Bcl-2 inhibitor as host directed therapy for pulmonary tuberculosis.

Sanjay Jain, Medha Singh, Mona Sarhan, Nerketa Damiba, Alok Singh, Andres Villabona-Rueda, Oscar Nino Meza, Xueyi Chen, Alvaro Ordonez, Franco D'Alessio and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Sanjay JainJohns Hopkins University School of Medicine.ORCID 0000-0001-9620-7070
Medha SinghJohns Hopkins University School of Medicine.
Mona SarhanJohns Hopkins University School of Medicine.
Nerketa DamibaJohns Hopkins University School of Medicine.
Alok SinghJohns Hopkins University School of Medicine.
Andres Villabona-RuedaJohns Hopkins University School of Medicine.
Oscar Nino MezaJohns Hopkins University School of Medicine.
Xueyi ChenJohns Hopkins University School of Medicine.
Alvaro OrdonezUniversity of Pennsylvania.ORCID 0000-0002-8571-0655
Franco D'AlessioJohns Hopkins University School of Medicine.
Eric AboagyeImperial College, London.
Laurence CarrollJohns Hopkins University School of Medicine.

Funding

Pharmacology and Pharmacometrics CoreP30AI168436 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MAUNANK SHAH · 2022 to 2026
$6.1M
Preclinical modeling to study Tuberculous MeningitisR01AI145435 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2020 to 2024
$4.0M
Measuring Intralesional Drug Exposures in Cavitary TB using Noninvasive In Vivo PET ImagingR01AI153349 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2020 to 2024
$3.8M
7T Cryogen-Free Preclinical MRI for small animals to study infectious diseases in BSL-3 containmentS10OD030381 · OD · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2022 to 2022
$1.7M
Pro-apoptotic Drugs as Host-Directed Treatments for Pulmonary TuberculosisR56AI179012 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2024 to 2024
$818k
NIAID NIH HHS P30 AI168436NIAID NIH HHS R01 AI145435NIAID NIH HHS R01 AI153349NIAID NIH HHS R56 AI179012NIH HHS S10 OD030381
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39281866
PMCPMC11398574

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.