Evidence map›Paper›PMID 39281842›Full record

ArticleGynecologic oncology reports2024

Near fatal case of mirvetuximab soravtansine-gynx induced interstitial lung disease and a review of the primary literature.

Joshua Clark, Andrew Blake, Scott Vasher, Richard C Boucher, Alexis R Jones, Hee Jae Choi, Benjamin B Albright

Abstract readCase Reports
In one paragraph

Article in Gynecologic oncology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joshua ClarkUniversity of North Carolina - Chapel Hill, Division of Pulmonary and Critical Care Medicine, USA.
Andrew BlakeUniversity of North Carolina - Chapel Hill, Division of Pulmonary and Critical Care Medicine, USA.
Scott VasherUniversity of North Carolina - Chapel Hill, Division of Pulmonary and Critical Care Medicine, USA.
Richard C BoucherUniversity of North Carolina - Chapel Hill, Division of Pulmonary and Critical Care Medicine, USA.
Alexis R JonesUniversity of North Carolina - Chapel Hill, Division of Gynecology Oncology, USA.
Hee Jae ChoiUniversity of North Carolina - Chapel Hill, Division of Pulmonary and Critical Care Medicine, USA.
Benjamin B AlbrightUniversity of North Carolina - Chapel Hill, Division of Gynecology Oncology, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

•Mirvetuximab soravtansine-gynx should be recognized as a cause of drug-induced interstitial lung disease (ILD).•Radiographic manifestations of mirvetuximab soravtansine-gyn induced ILD include organizing pneumonia pattern.•Interstitial lung disease related to mirvetuximab soravtansine-gyn can cause high morbidity.•Corticosteroids are commonly used in drug-induced interstitial lung disease and should be considered when encountering ILD related to mirvetuximab.•Changes to manufacturer dosing guidelines for grade 1 pneumonitis related to mirvetuximab soravtansine-gyn need to be considered.

Identifiers

PMID39281842
PMCPMC11399687

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.