ArticleJournal of inflammation research2024
A Novel Inflammatory Marker: Relationship Between Red Cell Distribution Width/Albumin Ratio and Vascular Complications in Patients with Type 2 Diabetes Mellitus.
Article in Journal of inflammation research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Association of the red blood cell distribution width-to-albumin ratio with incident depression and depressive symptom trajectories in older adults.European archives of psychiatry and clinical neuroscience · 2026Article
- Article
- A retrospective cohort study on the association between RAR and mortality in peritoneal Dialysis patients.BMC nephrology · 2026Article
- Diabetic retinopathy Is associated with histologic severity of diabetic kidney disease and systemic inflammation.Acta diabetologica · 2026Article
- The association between the red blood cell distribution width-to-albumin ratio and in-hospital mortality in cardiac arrest patients: an analysis of the eICU database.Frontiers in cardiovascular medicine · 2026Article
- Preoperative red cell width distribution to albumin ratio predicts early radial artery occlusion following coronary intervention via conventional transradial access.Scientific reports · 2025Article
- Association of red blood cell distribution width/albumin ratio with renal prognosis among patients with type 2 diabetes mellitus: A retrospective cohort study.Journal of diabetes investigation · 2025Article
- Association between red cell distribution width and its ratio with albumin and diabetic nephropathy/retinopathy: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2025Review
- Association Between Hemoglobin-to-Red Blood Cell Distribution Width Ratio and Arterial Stiffness.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Red cell distribution width-to-albumin ratio and hypertension risk: age-specific threshold effects identified in the 2017-2020 NHANES U.S. Adult population.BMC cardiovascular disorders · 2025Article
- The Red Blood Cell Distribution Width-to-Albumin Ratio's Role in Parkinson's Disease: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Prognostic significance of red cell distribution width to albumin ratio in ICU patients with Non-alcoholic fatty liver disease: a retrospective analysis.BMC gastroenterology · 2025Article
- Proposed Novel Heart Failure Biomarkers and Their Association with Length of Hospital Stay and Mortality: A Retrospective Observational Pilot Study.Diagnostics (Basel, Switzerland) · 2025Article
- Cardiovascular disease and depression as mediators between red blood cell distribution width to albumin ratio and cognitive impairment in older adults.Frontiers in physiology · 2025Article
- Prognostic Implications of Red Blood Cell Distribution Width to Albumin Ratio in Myelofibrosis: A 10-Year Multicenter and Retrospective Study.Journal of inflammation research · 2025Article
- Association between red blood cell distribution width-to-albumin ratio and risk of low lean mass: A cross-sectional study of NHANES 1999-2018.Science progressArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To explore the relationship between Red cell distribution width/albumin ratio (RAR) and vascular complications, including atherosclerosis of the lower limbs, diabetic nephropathy(DN), and diabetic retinopathy(DR), in patients with type 2 diabetes mellitus(T2DM). Patients and Methods: The study included 427 patients with type 2 diabetes mellitus who were hospitalized in the Department of Endocrinology of the First Affiliated Hospital of Jinan University (Guangzhou, China) between April 1, 2022 and May 31, 2023. Baseline characteristics were displayed according to the quartiles of the RAR. Logistic regression analysis and receiver operating characteristic curves (ROC) were used to analyze the data. Results: After adjusting for confounders, a higher RAR quartile(the fourth quartile) was associated with an increased risk of atherosclerosis of the lower limbs(OR: 2.973, 95% CI 1.281-6.906, p = 0.011), and diabetic nephropathy(OR: 2.876, 95% CI 1.315-6.287, p = 0.008) compared to the lowest RAR quartile. The patients were further divided into two groups according to urinary albumin to creatinine ratio (UACR≥30mg/g and UACR < 30mg/g) and Glomerular Filtration Rate (eGFR<60 mL·min⁻¹ (1.73 m²) ⁻¹ and eGFR≥60 mL·min⁻¹ (1.73 m²) ⁻¹). Similar results were observed. However, We found that RAR quartile did not significantly increase the likelihood of developing diabetic retinopathy(OR: 1.183, 95% CI 0.633-2.211, p = 0.598). Conclusion: The RAR ratio is associated with an increased risk of atherosclerosis of the lower limbs and diabetic nephropathy in patients with T2DM. The RAR ratio may be an important clinical marker of vascular complications in T2DM.
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