Evidence map›Paper›PMID 39281733›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Dynamic Contrast Enhanced MRI Mapping of Vascular Permeability for Evaluation of Breast Cancer Neoadjuvant Chemotherapy Response Using Image-to-Image Conditional Generative Adversarial Networks.

Chad A Arledge, Alan H Zhao, Umit Topaloglu, Dawen Zhao

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chad A ArledgeDepartment of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
Alan H ZhaoUniversity of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Umit TopalogluClinical and Translational Research Informatics Branch, National Cancer Institute, Rockville, MD 20850, USA.
Dawen ZhaoDepartment of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Convertible MRI contrast signaling delivery and release of anti-glioma nano-drugR01CA194578 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ZHAO, DAWEN · 2015 to 2019
$1.8M
NCI NIH HHS P30 CA012197NCI NIH HHS R01 CA194578
6 · The paper itself

Abstract

Dynamic contrast enhanced (DCE) MRI is a non-invasive imaging technique that has become a quantitative standard for assessing tumor microvascular permeability. Through the application of a pharmacokinetic (PK) model to a series of T1-weighed MR images acquired after an injection of a contrast agent, several vascular permeability parameters can be quantitatively estimated. These parameters, including K

Indexed as

breast cancerDynamic contrast enhanced (DCE) MRIimage-to-image conditional generative adversarial network (cGAN)neoadjuvant chemotherapy (NACT)vascular permeability

Identifiers

PMID39281733
PMCPMC11398591

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.