Evidence map›Paper›PMID 39281341›Full record

ArticleCurrent research in food science2024

Sprouting facilitates the antiglycative effect of black soybean (

Qian Zhou, Yuxuan Chen, Lifang Peng, Jun Wu, Wen Hao, Mingfu Wang

Abstract read
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Article in Current research in food science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Qian ZhouState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China.
Yuxuan ChenSchool of Biological Sciences, The University of Hong Kong, 999077 China.
Lifang PengSchool of Biological Sciences, The University of Hong Kong, 999077 China.
Jun WuInstitute for Advanced Study, Shenzhen University, Shenzhen 518060, China.
Wen HaoQingdao Municipal Center for Disease Control and Prevention, Qingdao 266000, China.
Mingfu WangShenzhen Key Laboratory of Food Nutrition and Health, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The exposure of advanced glycation end products (AGEs) can induce chronic inflammation, oxidative stress, and accelerated aging, contributing the onset and progression of many diseases especially diabetic complications. Therefore, the searching of antiglycative foods is of practical significance, which may serve as a strategy in the attenuation of AGEs-associated diseases. In this study, we evaluated the antiglycative potential of some beans and bean sprouts that were common in our daily life. The results revealed that sprouting enhanced the antiglycative activity of beans, with black soybean sprouts demonstrating the highest efficacy (4.92-fold higher than the unsprouted beans). To assess practical implications, we examined the antiglycative activity of black soybean sprouts in pork soup, a popular food model that incorporates sprouts. Our findings confirmed the inhibitory effect on a dose-dependent manner. Through open column fractionation, we identified isoflavones and soyasaponin Bb as the candidates responsible for these effects. Additionally, compare to the unsprouted black soybeans, we found significant increases in the levels of antioxidative properties (2.51-fold), total phenolics (7.28-fold), isoflavones, and soyasaponin Bb during the sprouting process. Further studies determined that genistein, genistin, and daidzin were the major antiglycative compounds in black soybean sprouts. Collectively, this study emphasizes the benefits of sprouted beans and offers foundation for the development of functional sprouting foods.

Indexed as

Advanced glycation end products (AGEs)AntioxidantDaidzinGenisteinGenistinMeat-sprout soup

Identifiers

PMID39281341
PMCPMC11399799

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.