Evidence map›Paper›PMID 39281273›Full record

ReviewFrontiers in pharmacology2024

A U.S. Pharmacopeia (USP) overview of Pan American botanicals used in dietary supplements and herbal medicines.

Roy Upton, Ignacio Agudelo, Yadira Cabrera, Armando Caceres, Angela Calderón, Fernando Calzada, Rosa Camacho, Fernando da Costa, Cecilia Dobrecky, Roberto Enciso and 28 more

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Plants (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Characterization of PMScientific reports · 2025
    Article
  6. Life (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Roy UptonAmerican Herbal Pharmacopoeia, Scotts Valley, CA, United States.
Ignacio AgudeloFacultad de Farmacia y Bioquímica, Departamento de Farmacología, Cátedra de Farmacobotánica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Yadira CabreraMinisterio de Salud Publica del Ecuador, Cuenca, Ecuador.
Armando CaceresLaboratorios Farmaya, Ciudad de Guatemala, Guatemala.
Angela CalderónDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL, United States.
Fernando CalzadaUnidad de Investigación Médica en Farmacología, UMAE Hospital de Especialidades 2 Piso CORSE, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Cuidad de Mexico, Mexico.
Rosa CamachoDireccion General de Medicamentos, Insumos y Drogas (DIGEMID), Ministerio de Salud Publica del Peru, Lima, Peru.
Fernando da CostaFaculdade de Ciencias Farmaceuticas de Ribeirao Preto, Universidad de Sao Paulo, Ribeirao Preto, Brazil.
Cecilia DobreckyUniversidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Tecnología Farmacéutica, Cátedra de Tecnología Farmacéutica I, Buenos Aires, Argentina.
Roberto EncisoFarmacopea de los Estados Unidos Mexicanos, Cuidad de Mexico, Mexico.
Marcela EscobarFacultad de Farmacia, Universidad de Valparaiso, Valparaiso, Chile.
Mina FakharyPharmavite LLC, Valencia, CA, United States.
Edward FletcherNative Botanicals Inc., Banner Elk, NC, United States.
Quanyin GaoHerbalife, Quality Control Labs, Los Angeles, CA, United States.
Olga LockFederacion Latinoamericana de Asociaciones Quimicas (FLAQ), Lima, Peru.
Rachel MataFacultad de Quimica, Universidad Autonoma de Mexico (UNAM), Cuidad de Mexico, Mexico.
Mirtha ParadaAgencia Nacional de Medicamentos (ANAMED), Instituto de Salud Publica de Chile, Gran Santiago, Chile.
Wilmer PereraCAMAG Scientific Inc., Wilmington, NC, United States.
Luis Miguel PomboCentro de Investigacion Fundacion Universitaria Juan N. Corpas, Bogota, Colombia.
Eike ReichCAMAG Laboratory, Muttenz, Switzerland.
Eric SanchezMedical Sciences Campus, University of Puerto Rico, San Juan, PR, United States.
Mario Juan SimirgiotisInstituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile.
Christian SoodThe Reena Group, Mississauga, Canada.
Virginie Treyvaud AmiguetHealth Canada, Ottawa, ON, Canada.
Martha VillarCentro de Investigación Clínica de Medicina Complementaria (CICMEC), Gerencia de Medicina Complementaria, Seguro Social de Salud-EsSalud and Departamento de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad Mayor de San Marcos, Lima, Peru.
Ricardo GhelmanNatural Products Committee of the Brazilian Academic Consortium or Integrative Health (CABSIN), San Pablo, Brazil.
Mariana Cabral SchveitzerNatural Products Committee of the Brazilian Academic Consortium or Integrative Health (CABSIN), San Pablo, Brazil.
Caio Fábio Schlechta PortellaNatural Products Committee of the Brazilian Academic Consortium or Integrative Health (CABSIN), San Pablo, Brazil.
Adriana WolffenbüttelNatural Products Committee of the Brazilian Academic Consortium or Integrative Health (CABSIN), San Pablo, Brazil.
Bettina RuppeltNatural Products Committee of the Brazilian Academic Consortium or Integrative Health (CABSIN), San Pablo, Brazil.
Fabiana Souza FrickmannNatural Products Committee of the Brazilian Academic Consortium or Integrative Health (CABSIN), San Pablo, Brazil.
Janette Gavillan-SuarezTRAMIL Program, San Jose, PR, United States.
Kristin AllenDepartment of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL, United States.
Luis Diego AlvaradoDepartment of Chemistry, University of Costa Rica (UCR), Bioactivity & Sustainable Development (BIODESS) Group, San Jose, Costa Rica.
Nandakumara SarmaDepartment of Chemistry, University of Costa Rica (UCR), Bioactivity & Sustainable Development (BIODESS) Group, San Jose, Costa Rica.
Robin MarlesUnited States Pharmacopeia (USP) Botanical Dietary Supplements and Herbal Medicines Expert Committee, United States Pharmacopeia (USP), Rokcville, MD, United States.
Maria MonagasUnited States Pharmacopeial Convention (USP), Dietary Supplements and Herbal Medicines, Rockville, MD, United States.
Mirtha Navarro-HoyosDepartment of Chemistry, University of Costa Rica (UCR), Bioactivity & Sustainable Development (BIODESS) Group, San Jose, Costa Rica.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The United States Pharmacopeial Convention (USP) is a nonprofit, scientific, standard-setting organization, and world leader in establishing quality, purity, and testing standards for medicines, foods, and dietary supplements. USP quality standards are used in more than 140 countries and are legally recognized by more than 40 countries. Currently, there is renewed interest in herbal medicines globally, and health policies are being implemented worldwide for the use of complementary and traditional medicine. In response, USP has developed a robust body of monographs that can be used to guide industry and regulators in ensuring the quality and safety of botanical ingredients used in dietary supplements and herbal medicines. Throughout the Pan American regions, there is a strong tradition of using botanicals as herbal medicines and, as in other regions, a growing desire for botanical dietary supplements. This underscores the need for public quality standards to ensure quality, reduce the flow of substandard and adulterated products, and ensure public health and safety. In April 2022, USP launched the Pan America Botanical Dietary Supplements and Herbal Medicines Expert Panel, with experts representing 12 different countries. The Expert Panel's work focuses on developing quality control standards for the most important botanical ingredients used in the respective countries, ingredients that are also of global importance. This article provides an overview of the state of botanical dietary supplements and herbal medicines in different Pan American regions with a focus on the regulatory status of herbal products, the development of national quality and research initiatives, and policies related to agriculture conservation and sustainability, among other topics.

Indexed as

botanicalsdietary supplementsherbal medicinesqualitystandards

Identifiers

PMID39281273
PMCPMC11392873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.