Evidence map›Paper›PMID 39281272›Full record

ArticleFrontiers in pharmacology2024

Efficacy and safety of Ginkgolide with intravenous alteplase thrombolysis in acute ischemic stroke with large vessel occlusion: a subgroup analysis of GIANT.

Zheyu Zhang, Wansi Zhong, Xuting Zhang, Xiaodong Ma, Xudong Lu, Meixia Zhang, Anyang Tao, Bing Zhang, Min Lou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zheyu ZhangDepartment of Neurology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Wansi ZhongDepartment of Neurology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Xuting ZhangDepartment of Neurology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Xiaodong MaDepartment of Neurology, Haiyan People's Hospital, Jiaxing, China.
Xudong LuDepartment of Neurology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China.
Meixia ZhangDepartment of Neurology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Anyang TaoDepartment of Neurology, The First People's Hospital of Taizhou, Taizhou, China.
Bing ZhangDepartment of Neurology, Huzhou Central Hospital, Huzhou, China.
Min LouDepartment of Neurology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: This study aims to explore the effectiveness and safety of Ginkgolide Methods: Ginkgolide with Intravenous Alteplase Thrombolysis in Acute Ischemic Stroke Improving Neurological Function (GIANT) was an open-label, prospective, multicenter, cluster-randomized clinical trial and included AIS patients in 24 centers randomized to the intervention of intravenous Ginkgolide Results: A total of 1,113 patients were included, with 268/913 (29.4%) presenting LVO and 508 (45.6%) presenting moderate-to-severe stroke. In patients with LVO, Ginkgolide Conclusion: Using Ginkgolide

Indexed as

acute ischemic strokeGinkgolideintravenous alteplaselarge vessel occlusionminor stroke

Identifiers

PMID39281272
PMCPMC11392837

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.