Evidence map›Paper›PMID 39281102›Full record

ArticleEClinicalMedicine2024

Detection of thyroid cancer among children and adolescents in Fukushima, Japan: a population-based cohort study of the Fukushima Health Management Survey.

Hideto Takahashi, Seiji Yasumura, Kunihiko Takahashi, Tetsuya Ohira, Hiroki Shimura, Hitoshi Ohto, Satoru Suzuki, Shinichi Suzuki, Tetsuo Ishikawa, Satoshi Suzuki and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EClinicalMedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hideto TakahashiTeikyo Heisei University, Tokyo, Japan.
Seiji YasumuraDepartment of Public Health, Fukushima Medical University School of Medicine, Fukushima, Japan.
Kunihiko TakahashiDepartment of Biostatistics, M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan.
Tetsuya OhiraDepartment of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Hiroki ShimuraDepartment of Laboratory Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
Hitoshi OhtoRadiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan.
Satoru SuzukiFukushima Global Medical Science Center, Fukushima Medical University, Fukushima, Japan.
Shinichi SuzukiDepartment of Surgery, Japan Community Healthcare Organization (JCHO), Nihonmatsu Hospital, Nihonmatsu, Japan.
Tetsuo IshikawaDepartment of Radiation Physics and Chemistry, Fukushima Medical University School of Medicine, Fukushima, Japan.
Satoshi SuzukiFukushima Global Medical Science Center, Fukushima Medical University, Fukushima, Japan.
Enbo MaHealth Promotion Center, Fukushima Global Medical Science Center, Fukushima Medical University, Fukushima, Japan.
Masanori NagaoDepartment of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Susumu YokoyaThyroid and Endocrine Center, Fukushima Medical University, Fukushima, Japan.
Kenji KamiyaRadiation Effects Research Foundation, Hiroshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Thyroid ultrasound examinations using a cohort study design (from the Fukushima Health Management Survey [FHMS]) were conducted after the nuclear power plant accident caused by the Great East Japan Earthquake in 2011. This study investigated the association between radiation exposure and the detection of thyroid cancer in children and adolescents. Methods: The cohort study has been conducted in Fukushima prefecture in Japan since 2011. The primary outcome was the external dose. We enrolled 253346 examinees who lived in Fukushima at the time of the accident (Dataset A), including 113120 examinees who had data on external radiation exposure (ERE) (Dataset B). The median dose in the examinee's district was used for missing dose. The association between ERE and detection of thyroid cancer or suspected thyroid cancer was analyzed using Poisson regressions with two types of explanatory variables: sex, age, overweight status, and district (Model 1), and past medical history, family history of thyroid cancer, frequency of seafood consumption, and frequency of seaweed consumption in addition to Model 1 (Model 2). Findings: During the second and third rounds of examinations, a total of 97 thyroid patients were detected, for a detection rate of 10.328 [ Interpretation: Our study showed no association between radiation exposure with extremely low dose which were more than 99.9% of all the exposure was less than 5 mSv, and thyroid cancer detection, when the follow-up period was an average of 3.7 years at the present, using the cohort study design. Funding: The National Health Fund for Children and Adults Affected by Nuclear Incidents in Japan.

Indexed as

Cohort studyDetection rateFull-scale thyroid (second- and third-round) examinationsJapan Fukushima Health Management Survey

Identifiers

PMID39281102
PMCPMC11400584

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.