Evidence map›Paper›PMID 39280750›Full record

ArticleRadiology case reports2024

Diminishing calcifications as a potential predictor of pancreatic ductal adenocarcinoma arising in association with IPMN in patients with chronic pancreatitis.

Mohammad Yasrab, Ryan C Rizk, Felipe Lopez-Ramirez, Taha M Ahmed, Alejandra Blanco, Ammar A Javed, Linda C Chu, Elliot K Fishman, Satomi Kawamoto

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PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Mohammad YasrabDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Ryan C RizkDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Felipe Lopez-RamirezDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Taha M AhmedDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Alejandra BlancoDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Ammar A JavedDepartment of Surgery, New York University Langone Hospital, New York, NY, USA.
Linda C ChuDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Elliot K FishmanDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Satomi KawamotoDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic pancreatitis (CP) is a progressive benign fibroinflammatory condition involving repeated episodes of pancreatic inflammation, which lead to fibrotic tissue replacement and subsequent pancreatic insufficiency. A lifetime risk of developing pancreatic ductal adenocarcinoma (PDAC) in patients with chronic pancreatitis is reported to be 1.5%-4%. However, diagnosis of PDAC in patients with CP can be challenging, in part due to overlapping imaging features. In rare instances, pancreatic parenchymal calcifications that are typically associated with chronic pancreatitis may diminish in the case of a developing PDAC. In this article, we present a patient with chronic pancreatitis in whom calcifications decreased at the time of pancreatic ductal adenocarcinoma diagnosis, as compared to prior CT imaging. The unique imaging features of "diminishing calcifications" associated with a hypoattenuating lesion can potentially be a useful sign of pancreatic ductal adenocarcinoma and may aid in early diagnosis and prompt treatment intervention.

Indexed as

Chronic pancreatitisComputed tomographyDiminishing calcificationIntraductal papillary mucinous neoplasmPancreatic ductal adenocarcinomaPancreatic neoplasms

Identifiers

PMID39280750
PMCPMC11399793

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