Evidence map›Paper›PMID 39280467›Full record

ArticleCureus2024

Development of Subcutaneous Panniculitis-Like T-cell Lymphoma After Immune Checkpoint Inhibitor Treatment.

Tommy Y Yu, Zartash Gul, Alicia M Hunt, Michael J Williams, Alexander M Maley

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tommy Y YuDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, USA.
Zartash GulDepartment of Oncology, Aurora St. Luke's Medical Center, Milwaukee, USA.
Alicia M HuntDepartment of Pathology and Laboratory Medicine, Aurora St. Luke's Medical Center, Milwaukee, USA.
Michael J WilliamsDepartment of Pharmacy, Aurora St. Luke's Medical Center, Milwaukee, USA.
Alexander M MaleyDepartment of Dermatology, Aurora St. Luke's Medical Center, Milwaukee, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Program death 1 (PD-1) inhibitors such as nivolumab are immune checkpoint inhibitors that have revolutionized the treatment of metastatic melanoma. Despite its success in treating melanoma, immune activation can lead to immune-related adverse effects, which are experienced by half of melanoma patients treated with PD-1 inhibitors. Despite the common frequency of immune-mediated adverse events, the development of a secondary lymphoma is exceedingly rare. We present the case of a 53-year-old woman diagnosed with stage IV metastatic melanoma, treated with nivolumab, who subsequently developed fatal subcutaneous panniculitis-like T-cell lymphoma (SPTCL).

Indexed as

cancer immunotherapycutaneous t-cell lymphomaimmune checkpoint inhibitormelanoma treatmentnivolumab-related adverse events

Identifiers

PMID39280467
PMCPMC11402492

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.