Evidence map›Paper›PMID 39280209›Full record

ReviewCurrent therapeutic research, clinical and experimental2024

Impact of Magnesium Supplementation on Blood Pressure: An Umbrella Meta-Analysis of Randomized Controlled Trials.

Abdullah M Alharran, Mooza M Alzayed, Parsa Jamilian, Kousalya Prabahar, Aminah Hassan Kamal, Muteb N Alotaibi, Omar E Elshaer, Mshal Alhatm, Mohd Diya Masmoum, Benjamin Hernández-Wolters and 3 more

Abstract readReview
In one paragraph

Review in Current therapeutic research, clinical and experimental, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Abdullah M AlharranCollege of Medicine & Medical Sciences, Arabian Gulf University, Manama, Bahrain.
Mooza M AlzayedCollege of Medicine & Medical Sciences, Arabian Gulf University, Manama, Bahrain.
Parsa JamilianSchool of Medicine, Keele University, Staffordshire, United Kingdom.
Kousalya PrabaharDepartment of Pharmacy Practice, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia.
Aminah Hassan KamalDepartment of Adult Cardiology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.
Muteb N AlotaibiCollege of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Omar E ElshaerCollege of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Mshal AlhatmCollege of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Mohd Diya MasmoumCollege of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Benjamin Hernández-WoltersUniversity Center for Health Science, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico.
Raghad SindiFaculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Hamed Kord-VarkanehDepartment of Nutrition and Food Hygiene, School of Medicine, Nutrition Health Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Ahmed Abu-ZaidCollege of Medicine, Alfaisal University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: Conflicting results on the effect of magnesium supplementation on blood pressure have been published in previous meta-analyses; hence, we conducted this umbrella meta-analysis of RCTs to provide a more robust conclusion on its effects. Methods: Four databases including PubMed, Scopus, EMBASE, and Web of Science were searched to find pertinent papers published on international scientific from inception up to July 15, 2024. We utilized STATA version 17.0 to carry out all statistical analyses (Stata Corporation, College Station, TX, US). The random effects model was used to calculate the overall effect size ES and CI. Findings: Ten eligible review papers with 8610 participants studied the influence of magnesium on SBP and DBP. The pooling of their effect sizes resulted in a significant reduction of SBP (ES = -1.25 mmHg; 95% CI: -1.98, -0.51, Implications: The findings of the present umbrella meta-analysis showed an overall decrease of SBP and DBP with magnesium supplementation, particularly at doses of ≥400 mg/day for ≥12 weeks.

Indexed as

blood pressuremagnesiumsystematic reviewumbrella of meta-analysis

Identifiers

PMID39280209
PMCPMC11401110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.