Evidence map›Paper›PMID 39280192›Full record

ArticleBiomicrofluidics2024

An

Emily J Jones, Benjamin M Skinner, Aimee Parker, Lydia R Baldwin, John Greenman, Simon R Carding, Simon G P Funnell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomicrofluidics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emily J JonesFood, Microbiome and Health Research Programme, Quadram Institute, Norwich, United Kingdom.ORCID https://orcid.org/0000-0002-3040-1353
Benjamin M SkinnerSchool of Life Sciences, University of Essex, Colchester, United Kingdom.ORCID https://orcid.org/0000-0002-7152-1167
Aimee ParkerFood, Microbiome and Health Research Programme, Quadram Institute, Norwich, United Kingdom.ORCID https://orcid.org/0000-0003-1765-9656
Lydia R BaldwinCentre of Biomedical Sciences, Hull York Medical School, University of Hull, Hull, United Kingdom.ORCID https://orcid.org/0009-0006-4047-9775
John GreenmanCentre of Biomedical Sciences, Hull York Medical School, University of Hull, Hull, United Kingdom.ORCID https://orcid.org/0000-0002-6003-6051
Simon R CardingORCID https://orcid.org/0000-0002-2383-9701
Simon G P FunnellORCID https://orcid.org/0000-0002-4254-2751

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The death of dopamine-producing neurons in the substantia nigra in the base of the brain is a defining pathological feature in the development of Parkinson's disease (PD). PD is, however, a multi-systemic disease, also affecting the peripheral nervous system and gastrointestinal tract (GIT) that interact via the gut-brain axis (GBA). Our dual-flow GIT-brain microphysiological system (MPS) was modified to investigate the gut-to-brain translocation of the neurotoxin trigger of PD, 1-methyl-4-phenylpyridinium (MPP

Identifiers

PMID39280192
PMCPMC11401645

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.