Evidence map›Paper›PMID 39279936›Full record

ArticleJournal of gastrointestinal oncology2024

Pancreatic cancer mortality trends in the United States: how much have we moved the needle?

Jia Yi Tan, Yong Hao Yeo, Wern Lynn Ng, Cho Han Chiang, Chee-Chee Stucky, Nabil Wasif, Zhi Ven Fong

Abstract read
In one paragraph

Article in Journal of gastrointestinal oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. Article
  6. Pancreatic cancer: a haystack of needles.Journal of gastrointestinal oncology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jia Yi TanDepartment of Internal Medicine, New York Medical College at Saint Michael's Medical Center, Newark, NJ, USA.ORCID https://orcid.org/0009-0002-7983-2928
Yong Hao YeoDepartment of Internal Medicine/Pediatrics, Corewell Health, Royal Oak, MI, USA.ORCID https://orcid.org/0000-0001-5559-7236
Wern Lynn NgDepartment of Internal Medicine, University of Pittsburgh Medical Center (UPMC) Harrisburg, Harrisburg, PA, USA.ORCID https://orcid.org/0000-0003-2230-1376
Cho Han ChiangDepartment of Medicine, Mount Auburn Hospital, Harvard Medical School, Cambridge, MA, USA.ORCID https://orcid.org/0000-0002-5757-6161
Chee-Chee StuckyDivision of Surgical Oncology and Endocrine Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA.
Nabil WasifDivision of Surgical Oncology and Endocrine Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA.
Zhi Ven FongDivision of Surgical Oncology and Endocrine Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA.ORCID https://orcid.org/0000-0001-6398-413X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite advances made in pancreatic cancer treatment, the extent of progress made in pancreatic cancer mortality at the population level remains unclear. Our cross-sectional study sought to measure trends in pancreatic cancer mortality in the United States in the last 2 decades. Methods: Patients with pancreatic cancer mortality from 1999 to 2020 were analyzed from the Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER). Age-adjusted mortality rates (AAMRs) per 100,000 individuals were measured. We used joinpoint trend analysis to determine average annual percent change (AAPC) in AAMR trends. Results: From 1999 to 2020, pancreatic cancer accounted for 809,197 deaths. Overall, the AAMRs of pancreatic cancer increased from 20.74 per 100,000 individuals in 1999 to 21.60 per 100,000 individuals in 2020. The highest AAMR was recorded in non-Hispanic Black males (30.11 per 100,000 individuals), and the lowest, in non-Hispanic White females (18.51 per 100,000 individuals). Patients aged 75-84 years had the highest AAMR (6.87 per 100,000 individuals) compared to the younger patients. The highest AAMR was observed in the Northeast region (22.07 per 100,000 individuals) and rural regions (21.29 per 100,000 individuals). Conclusions: There was no improvement in pancreatic cancer mortality in the last two decades. These findings emphasize the importance of efforts to increase access to multidisciplinary cancer care with the realization that without it, improvements in treatment standards will not translate to lower cancer mortality at the population level.

Indexed as

cancerepidemiologygastroenterologyoncologyPancreatic cancer

Identifiers

PMID39279936
PMCPMC11399823

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.