Evidence map›Paper›PMID 39279450›Full record

ArticleHaematologica2025

Intra-marrow delivery of human interleukin-6-loaded biodegradable microspheres promotes growth of patientderived multiple myeloma cells in mice.

Manpreet Bariana, Weiwei Wang, Zhuozhuo Yin, Jingyu Sun, Shabnam Samimi, Shaina A Anuncio, Elena Cassella, Nuo Xu, Wei Hu, Ariel Aptekmann and 4 more

Abstract read
In one paragraph

Article in Haematologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Manpreet BarianaCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA; Hackensack Meridian School of Medicine, Nutley, NJ.
Weiwei WangDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ, USA; School of Life Sciences, Yantai University, Yantai, Shandong.
Zhuozhuo YinDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ.
Jingyu SunDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ.
Shabnam SamimiCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA; Department of Chemistry and Chemical Biology, Stevens Institute of Technology, Hoboken, NJ.
Shaina A AnuncioCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ.
Elena CassellaCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ.
Nuo XuDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ.
Wei HuCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ.
Ariel AptekmannCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ.
David S SiegelCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA; Multiple Myeloma Division, John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ.
Kar F ChowDepartment of Pathology, Hackensack University Medical Center, Hackensack, NJ.
Hongjun WangDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ, USA; Semcer Center for Healthcare Innovation, Stevens Institute of Technology, Hoboken, NJ. hongjun.wang@stevens.edu.
Johannes L ZakrzewskiCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA; Hackensack Meridian School of Medicine, Nutley, NJ, USA; Department of Oncology, Georgetown University, Washington, DC, USA; Department of Pediatrics, Hackensack University Medical Center, Hackensack, NJ. johannes.zakrzewski@hmh-cdi.org.

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI Louis M Weiner · 1990 to 2026
$71.5M
Harnessing the thymus for long-term tumor control with hematopoietic stem cell-derived naive CAR T cellsR37CA250661 · NCI · HACKENSACK UNIVERSITY MEDICAL CENTER · PI Johannes Zakrzewski · 2022 to 2026
$2.7M
NCI NIH HHS P30 CA051008NCI NIH HHS R37 CA250661
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39279450
PMCPMC11788620

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.