Evidence map›Paper›PMID 39278924›Full record

ArticleInfectious diseases of poverty2024

Spatio-temporal dynamics of malaria in Rwanda between 2012 and 2022: a demography-specific analysis.

Felix K Rubuga, Paula Moraga, Ayman Ahmed, Emmanuel Siddig, Eric Remera, Giovenale Moirano, Guéladio Cissé, Jürg Utzinger

Abstract read
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Article in Infectious diseases of poverty, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Visceral leishmaniasis risk clusters on Brazil's borders: 2013 to 2022.Revista da Sociedade Brasileira de Medicina Tropical · 2026
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  3. Article
  4. Review
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Felix K RubugaSwiss Tropical and Public Health Institute, Allschwil, Switzerland. flxktm86@gmail.com.ORCID http://orcid.org/0000-0002-6375-9570
Paula MoragaComputer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.
Ayman AhmedSwiss Tropical and Public Health Institute, Allschwil, Switzerland.
Emmanuel SiddigDepartment of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Eric RemeraRwanda Biomedical Center, Kigali, Rwanda.
Giovenale MoiranoDepartment of Medical Science, University of Turin, Torino, Italy.
Guéladio CisséSwiss Tropical and Public Health Institute, Allschwil, Switzerland.
Jürg UtzingerSwiss Tropical and Public Health Institute, Allschwil, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite global efforts to reduce and eventually interrupt malaria transmission, the disease remains a pressing public health problem, especially in sub-Saharan Africa. This study presents a detailed spatio-temporal analysis of malaria transmission in Rwanda from 2012 to 2022. The main objective was to gain insights into the evolving patterns of malaria and to inform and tailor effective public health strategies.

methodsThe study used yearly aggregated data of malaria cases from the Rwanda health management information system. We employed a multifaceted analytical approach, including descriptive statistics and spatio-temporal analysis across three demographic groups: children under the age of 5 years, and males and females above 5 years. Bayesian spatially explicit models and spatio scan statistics were utilised to examine geographic and temporal patterns of relative risks and to identify clusters of malaria transmission.

resultsWe observed a significant increase in malaria cases from 2014 to 2018, peaking in 2016 for males and females aged above 5 years with counts of 98,645 and 116,627, respectively and in 2018 for under 5-year-old children with 84,440 cases with notable geographic disparities. Districts like Kamonyi (Southern Province), Ngoma, Kayonza and Bugesera (Eastern Province) exhibited high burdens, possibly influenced by factors such as climate, vector control practices, and cross-border dynamics. Bayesian spatially explicit modeling revealed elevated relative risks in numerous districts, underscoring the heterogeneity of malaria transmission in these districts, and thus contributing to an overall rising trend in malaria cases until 2018, followed by a subsequent decline. Our findings emphasize that the heterogeneity of malaria transmission is potentially driven by ecologic, socioeconomic, and behavioural factors.

conclusionsThe study underscores the complexity of malaria transmission in Rwanda and calls for climate adaptive, gender-, age- and district-specific strategies in the national malaria control program. The emergence of both artemisinin and pyrethoids resistance and persistent high transmission in some districts necessitates continuous monitoring and innovative, data-driven approaches for effective and sustainable malaria control.

Indexed as

Bayes TheoremMalariaSpatio-Temporal AnalysisAdolescentChildChild, PreschoolDemographyFemaleHumansInfantInfant, NewbornMaleRwandaEpidemiologyMalaria transmissionPublic healthRwandaSpatio-temporal analysis

Identifiers

PMID39278924
PMCPMC11403800

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.