Evidence map›Paper›PMID 39277825›Full record

Observational studyExperimental physiology2024

Nocturnal pulse oximetry for the detection and prediction of acute mountain sickness: An observational study.

Kelsey E Joyce, Kimberly Ashdown, John P Delamere, Chris Bradley, Christopher T Lewis, Abigail Letchford, Rebekah A I Lucas, Will Malein, Owen Thomas, Arthur R Bradwell and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Experimental physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kelsey E JoyceSchool of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-3189-847X
Kimberly AshdownBirmingham Medical Research Expeditionary Society, University of Birmingham, Birmingham, UK.
John P DelamereBirmingham Medical Research Expeditionary Society, University of Birmingham, Birmingham, UK.
Chris BradleySchool of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.
Christopher T LewisBirmingham Medical Research Expeditionary Society, University of Birmingham, Birmingham, UK.
Abigail LetchfordBirmingham Medical Research Expeditionary Society, University of Birmingham, Birmingham, UK.
Rebekah A I LucasSchool of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-6644-3838
Will MaleinBirmingham Medical Research Expeditionary Society, University of Birmingham, Birmingham, UK.
Owen ThomasBirmingham Medical Research Expeditionary Society, University of Birmingham, Birmingham, UK.
Arthur R BradwellBirmingham Medical Research Expeditionary Society, University of Birmingham, Birmingham, UK.
Samuel J E LucasSchool of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-8713-2457

Funding

Jabbs Foundation (The Jabbs Foundation) 1128402
6 · The paper itself

Abstract

Acute mountain sickness (AMS) is a well-studied illness defined by clinical features (e.g., headache and nausea), as assessed by the Lake Louise score (LLS). Although obvious in its severe form, early stages of AMS are poorly defined and easily confused with common travel-related conditions. Measurement of hypoxaemia, the cause of AMS, should be helpful, yet to date its utility for identifying AMS susceptibility remains unclear. This study quantified altitude-induced hypoxaemia in individuals during an ascent to 4800 m to determine the utility of nocturnal pulse oximetry measurements for prediction of AMS. Eighteen individuals (36 ± 16 years of age) ascended to 4800 m over 12 days. Symptomology of AMS was assessed each morning via LLS criteria, with participants categorized as either AMS-positive (LLS ≥ 3 with headache) or AMS-negative. Overnight peripheral oxygen saturations (ov-

Indexed as

Altitude SicknessHypoxiaOximetryAcute DiseaseAdultAltitudeFemaleHumansMaleMiddle AgedOxygenOxygen SaturationYoung AdultOxygenhigh altitudehypoxiaperipheral oxygenationsleep

Identifiers

PMID39277825
PMCPMC11522851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.