Evidence map›Paper›PMID 39277731›Full record

ArticleBMC cardiovascular disorders2024

Early surgical outcome for Tetralogy Of Fallot In An African Setting; A Tanzanian experience using retrospective analysis of hospital data.

Naizihijwa Majani, Godwin Sharau, Vivienne Mlawi, Zawadi Kalezi, Stella Mongella, Nuru Letara, Deogratias Nkya, Sulende Kubhoja, Pilly Chillo, Martijn Slieker and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Naizihijwa MajaniDepartment of Pediatric Cardiology, Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania. naiz77@yahoo.com.ORCID 0000-0003-3101-8257
Godwin SharauDepartment of Pediatric Cardiac Surgery, Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania.
Vivienne MlawiDepartment of Pediatric Cardiac Surgery, Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania.ORCID 0000-0002-4152-5239
Zawadi KaleziDepartment of Pediatric Cardiology, Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania.ORCID 0000-0001-6784-437X
Stella MongellaDepartment of Pediatric Cardiology, Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania.ORCID 0000-0002-8029-8526
Nuru LetaraDepartment of Pediatric Cardiology, Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania.ORCID 0009-0005-4742-7620
Deogratias NkyaDepartment of Pediatrics, Muhimbili University of Health and Allied Sciences (MUHAS), Dar es Salaam, Tanzania.ORCID 0000-0002-0521-1208
Sulende KubhojaDepartment of Pediatric Cardiology, Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania.
Pilly ChilloFaculty of Medicine, Department of Internal Medicine, Muhimbili University of Health and Allied Sciences (MUHAS), Dar es Salaam, Tanzania.ORCID 0000-0001-7073-1122
Martijn SliekerDepartment of Pediatric Cardiology, Wilhelmina Children's Hospital, Utrecht, Netherlands.ORCID 0000-0001-8198-511X
Mohamed JanabiDepartment of Adult Cardiology, Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania.ORCID 0000-0001-9299-1785
Diederick GrobbeeJulius Global Health, Julius Center for Health Sciences and Primary Care, Utrecht, Netherlands.ORCID 0000-0003-4472-4468
Peter KisengeDepartment of Adult Cardiology, Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTetralogy of Fallot (TOF) is typically treated in infancy but often done late in many resource-limited countries, jeopardizing surgical outcomes. This study examined the early results of children undergoing primary complete TOF repair at the Jakaya Kikwete Cardiac Institute (JKCI) in Tanzania, an emerging cardiac center in Eastern Africa.

methodsA retrospective cohort study of children ≤ 18 years undergoing primary TOF complete repair between 2019 and 2021 was conducted. Patients with complex TOF and those with obvious genetic syndrome were excluded. Data on socio-demography, pre-and postoperative cardiac complications, Intensive Care Unit (ICU) and hospital stay, and in-hospital and 30-day mortality were analyzed. Logistic regressions were employed to find the factors for mortality, ICU, and hospital stays.

resultsThe I02 children underwent primary TOF complete repair were majority male (65.7%; n = 67), with a median age of 3.0 years (IQR: 2-6), ranging from 3 months to 17 years.Only 20 patients (19.6%) were below one year of age. Almost all (90%; n = 92) were underweight, with a mean BMI of 14.6 + 3.1 kg/m

conclusionTOF repairs in this African setting at a national cardiac referral hospital face challenges associated with patients' older age and compromised nutritional status during the surgery. Perioperative mortality rates and morbidity for patients operated at an older age remain elevated. It's important to address these issues to improve outcomes in these settings.

Indexed as

Cardiac Surgical ProceduresHospital MortalityLength of StayPostoperative ComplicationsTetralogy of FallotAdolescentChildChild, PreschoolFemaleHumansInfantMaleRetrospective StudiesRisk AssessmentRisk FactorsTanzaniaLow-middle-income settingSurgical outcomesTetralogy of fallot

Identifiers

PMID39277731
PMCPMC11401386

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.