Evidence map›Paper›PMID 39277636›Full record

ArticleScientific reports2024

Ensembling U-Nets for microaneurysm segmentation in optical coherence tomography angiography in patients with diabetic retinopathy.

Lennart Husvogt, Antonio Yaghy, Alex Camacho, Kenneth Lam, Julia Schottenhamml, Stefan B Ploner, James G Fujimoto, Nadia K Waheed, Andreas Maier

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Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Lennart HusvogtPattern Recognition Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058, Erlangen , Germany. Lennart.Husvogt@fau.de.
Antonio Yaghy *New England Eye Center, Tufts School of Medicine, Boston, MA, 02111, USA.
Alex Camacho *New England Eye Center, Tufts School of Medicine, Boston, MA, 02111, USA.
Kenneth LamNew England Eye Center, Tufts School of Medicine, Boston, MA, 02111, USA.
Julia SchottenhammlPattern Recognition Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058, Erlangen , Germany.
Stefan B PlonerPattern Recognition Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058, Erlangen , Germany.
James G FujimotoResearch Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Nadia K WaheedNew England Eye Center, Tufts School of Medicine, Boston, MA, 02111, USA.
Andreas MaierPattern Recognition Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058, Erlangen , Germany.

Funding

Deutsche Forschungsgemeinschaft 508075009
6 · The paper itself

Abstract

Diabetic retinopathy is one of the leading causes of blindness around the world. This makes early diagnosis and treatment important in preventing vision loss in a large number of patients. Microaneurysms are the key hallmark of the early stage of the disease, non-proliferative diabetic retinopathy, and can be detected using OCT angiography quickly and non-invasively. Screening tools for non-proliferative diabetic retinopathy using OCT angiography thus have the potential to lead to improved outcomes in patients. We compared different configurations of ensembled U-nets to automatically segment microaneurysms from OCT angiography fundus projections. For this purpose, we created a new database to train and evaluate the U-nets, created by two expert graders in two stages of grading. We present the first U-net neural networks using ensembling for the detection of microaneurysms from OCT angiography en face images from the superficial and deep capillary plexuses in patients with non-proliferative diabetic retinopathy trained on a database labeled by two experts with repeats.

Indexed as

Diabetic RetinopathyMicroaneurysmTomography, Optical CoherenceAngiographyFluorescein AngiographyHumansNeural Networks, ComputerRetinal Vessels

Identifiers

PMID39277636
PMCPMC11401926

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.