Evidence map›Paper›PMID 39277622›Full record

ArticleScientific reports2024

Assessing the toxicity of green Agaricus bisporus-based Cadmium Sulfide nanoparticles on Musca domestica as a biological model.

Hanan I Elhenawy, Noura A Toto, Abdelazeem S Eltaweil, Hussein K Hussein, Maria Augustyniak, Lamia M El-Samad

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hanan I Elhenawy *Department of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt.
Noura A TotoDepartment of Zoology, Faculty of Science, Damanhur University, Damanhur, Egypt.
Abdelazeem S EltaweilDepartment of Engineering, College of Engineering and Technology, University of Technology and Applied Sciences, Ibra, Sultanate of Oman.
Hussein K HusseinDepartment of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt.
Maria AugustyniakInstitute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Bankowa 9, 40-007, Katowice, Poland.
Lamia M El-Samad *Department of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt. lamya.moustafa@alexu.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The common housefly, Musca domestica, known for transmitting over 100 infections, was studied using green-synthesized Cadmium Sulfide nanoparticles (CdS NPs) from Agaricus bisporus. These CdS NPs were tested on third-instar larvae under laboratory conditions using dipping and feeding methods with concentrations (75, 100, 125, 150, 175, and 200 µg/mL). The toxicity, measured by LC50, was found to be 138 µg/mL for dipping treatment and 123 µg/mL for feeding treatment. Analysis with an energy-dispersive X-ray microanalyzer confirmed Cd accumulation in the larval midgut, indicating penetration of CdS NPs into the organism, which may potentially increase their toxicity. CdS NPs caused disruptions in Heat Shock Protein 70, cell apoptosis, and various biochemical components. Scanning electron microscopy revealed morphological abnormalities in larvae, pupae, and adults exposed to CdS NPs. Ultrastructural examination showed significant midgut tissue abnormalities in larvae treated with 123 µg/mL of CdS NPs. Our study demonstrated that green-synthesized CdS NPs from A. bisporus can effectively control the development of M. domestica larvae.

Indexed as

AgaricusCadmium CompoundsHousefliesLarvaSulfidesAnimalsMetal NanoparticlesModels, BiologicalNanoparticlesCadmium Compoundscadmium sulfideSulfidesAgaricus bisporusBiochemical componentsCadmium SulfideCell apoptosisHSP70 expressionMusca domestica

Identifiers

PMID39277622
PMCPMC11401898

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.