Evidence map›Paper›PMID 39277605›Full record

ArticleScientific reports2024

Effect of aortic valve replacement on myocardial perfusion and exercise capacity in patients with severe aortic stenosis.

Saadia Aslam, Abhishek Dattani, Aseel Alfuhied, Gaurav S Gulsin, Jayanth R Arnold, Christopher D Steadman, Michael Jerosch-Herold, Hui Xue, Peter Kellman, Gerry P McCann and 1 more

Abstract read
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In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Saadia AslamDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK. sa969@leicester.ac.uk.
Abhishek DattaniDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Aseel AlfuhiedDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Gaurav S GulsinDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Jayanth R ArnoldDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Christopher D SteadmanPoole Hospital NHS Foundation Trust, Poole, UK.
Michael Jerosch-HeroldDepartment of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Hui XueNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, USA.
Peter KellmanNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, USA.
Gerry P McCannDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Anvesha SinghDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.

Funding

Academy of Medical Sciences SGL018\1057British Heart Foundation FS/CRTF/20/24069British Heart Foundation PG/07/068/2334
6 · The paper itself

Abstract

Aortic valve replacement (AVR) leads to reverse cardiac remodeling in patients with aortic stenosis (AS). The aim of this secondary pooled analysis was to assess the degree and determinants of changes in myocardial perfusion post AVR, and its link with exercise capacity, in patients with severe AS. A total of 68 patients underwent same-day echocardiography and cardiac magnetic resonance imaging with adenosine stress pre and 6-12 months post-AVR. Of these, 50 had matched perfusion data available (age 67 ± 8 years, 86% male, aortic valve peak velocity 4.38 ± 0.63 m/s, aortic valve area index 0.45 ± 0.13cm

Indexed as

Aortic ValveAortic Valve StenosisExercise TestExercise ToleranceHeart Valve Prosthesis ImplantationAgedCoronary CirculationEchocardiographyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedSeverity of Illness IndexAortic stenosisAortic valve replacementExercise capacityMagnetic resonance imagingMyocardial perfusion reserve

Identifiers

PMID39277605
PMCPMC11401907

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.