ArticleNature communications2024
Biodegradable oxygen-evolving metalloantibiotics for spatiotemporal sono-metalloimmunotherapy against orthopaedic biofilm infections.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Research progress on T-cell responses inFrontiers in microbiology · 2026Pooled it
- Ultrasonic-activated LaFundamental research · 2026Article
- Sonosensitized Hemoglobin Nanoparticles for Ultrasound-Triggered NO Gas Therapy of Periodontitis.Nano letters · 2026Article
- Development of bacterial sonosensitizer hybrid systems to enhance cancer sono-immunotherapy.Acta pharmaceutica Sinica. B · 2026Article
- Emerging non-antibiotic strategies for implant-associated biofilm infections by reprogramming the dysregulated immune microenvironment.NPJ biofilms and microbiomes · 2026Review
- Neutrophil-based delivery platforms: from natural mechanisms to engineered therapeutics.Theranostics · 2026Review
- Advances in antibiofilm strategies for medical implant-associated infections: emerging technologies and translational challenges.Frontiers in microbiology · 2026Review
- Current advances in metal nanoparticle-based stimuli-responsive nanotherapies.Frontiers in chemistry · 2026Review
- Emerging Strategies for Antitumor Immunotherapy and Antiviral Defense Through the cGAS-STING Pathway.International journal of nanomedicine · 2026Review
- HJournal of nanobiotechnology · 2025Article
- Strategies and applications of antibacterial surface-modified biomaterials.Bioactive materials · 2025Review
- Macrophage-membrane-camouflaged nanoagents for precise bacterial clearance.Innovation (Cambridge (Mass.)) · 2025Review
- Hybrid Outer Membrane Vesicles with Genetically Engineering for Treatment of Implant-Associated Infections and Relapse Prevention Through Host Immunomodulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A multimodal defect-rich nanoreactor triggers sono-piezoelectric tandem catalysis and iron metabolism disruption for implant infections.Science advances · 2025Article
- The adaptability ofFrontiers in cellular and infection microbiology · 2025Review
- A novel strategy for treating orthopedic infection: Combination of sonodynamic therapy and immunotherapy.Biomaterials translational · 2025Article
- Nanozyme-Based Strategies against Bone Infection.Research (Washington, D.C.) · 2025Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Pathogen-host competition for manganese and intricate immunostimulatory pathways severely attenuates the efficacy of antibacterial immunotherapy against biofilm infections associated with orthopaedic implants. Herein, we introduce a spatiotemporal sono-metalloimmunotherapy (SMIT) strategy aimed at efficient biofilm ablation by custom design of ingenious biomimetic metal-organic framework (PCN-224)-coated MnO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.