Evidence map›Paper›PMID 39277185›Full record

ArticleOpen heart2024

Pretransplant cardiac stress testing and transplant wait time in kidney transplantation candidates.

Ming-Sum Lee, Columbus Batiste, James Onwuzurike, Rachid Elkoustaf, Yi-Lin Wu, Wansu Chen, Joseph Kahwaji, Amandeep Sahota, Roland L Lee

Abstract read
In one paragraph

Article in Open heart, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ming-Sum LeeDepartment of Cardiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, USA mingsum.lee@kp.org.ORCID 0000-0001-6121-6452
Columbus BatisteDepartment of Cardiology, Kaiser Permanente Riverside Medical Center, Riverside, California, USA.
James OnwuzurikeDepartment of Cardiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, USA.
Rachid ElkoustafDepartment of Cardiology, Kaiser Permanente Riverside Medical Center, Riverside, California, USA.
Yi-Lin WuDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.
Wansu ChenDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.
Joseph KahwajiKaiser Permanente Los Angeles Medical Center, Los Angeles, California, USA.
Amandeep SahotaKaiser Permanente Los Angeles Medical Center, Los Angeles, California, USA.
Roland L LeeKaiser Permanente Los Angeles Medical Center, Los Angeles, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRoutine screening for cardiovascular disease before kidney transplantation remains controversial. This study aims to compare cardiac testing rates in patients with end-stage renal disease, referred and not referred for transplantation, and assess the impact of testing on transplant wait times.

methodsThis is a retrospective cohort study of 22 687 end-stage renal disease patients from 2011 to 2022, within an integrated health system. Cardiac testing patterns, and the association between cardiac testing and transplant wait times and post-transplant mortality were evaluated.

resultsOf 22 687 patients (median age 66 years, 41.1% female), 6.9% received kidney transplants, and 21.0% underwent evaluation. Compared with dialysis patients, transplant patients had a 5.6 times higher rate of stress nuclear myocardial perfusion imaging with single-photon emission (rate ratio (RR) 5.64, 95% CI 5.37 to 5.92), a 6.5 times higher rate of stress echocardiogram (RR 6.51, 95% CI 5.65 to 7.51) and 16% higher cardiac catheterisation (RR 1.16, 95% CI 1.06 to 1.27). In contrast, revascularisation rates were significantly lower in transplant patients (RR 0.46, 95% CI 0.36 to 0.58). Transplant wait times were longer for patients who underwent stress testing (median 474 days with no testing vs 1053 days with testing) and revascularisation (1796 days for percutaneous intervention and 2164 days for coronary artery bypass surgery). No significant association was observed with 1-year post-transplant mortality (adjusted OR 1.99, 95% CI 0.46 to 8.56).

conclusionsThis study found a higher rate of cardiac testing in dialysis patients evaluated for kidney transplants. Cardiac testing was associated with longer transplant wait time, but no association was observed between testing and post-transplant mortality.

Indexed as

Exercise TestKidney Failure, ChronicKidney TransplantationWaiting ListsAgedCardiovascular DiseasesFemaleFollow-Up StudiesHumansMaleMiddle AgedMyocardial Perfusion ImagingPreoperative CareRetrospective StudiesRisk FactorsTime FactorsAtherosclerosisDiagnostic ImagingOutcome Assessment, Health Care

Identifiers

PMID39277185
PMCPMC11404252

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.