Evidence map›Paper›PMID 39276747›Full record

ArticleJournal of hazardous materials2024

Comprehensive model for predicting toxic equivalents (TEQ) reduction due to dechlorination of polychlorinated dibenzo-p-dioxin and dibenzofurans (PCDD/F congeners).

Dar Tafazul Islam, Maggie R Williams, Brian J Teppen, Cliff T Johnston, Hui Li, Stephen A Boyd, Gerben J Zylstra, Donna E Fennell, Alison M Cupples, Syed A Hashsham

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of hazardous materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dar Tafazul IslamDepartment of Civil and Environmental Engineering, Michigan State University, East Lansing, MI, USA.
Maggie R WilliamsSchool of Engineering and Technology, Institute for Great Lakes Research, Central Michigan University, Mount Pleasant, MI, USA.
Brian J TeppenDepartment of Plant, Soil and Microbial Sciences, Michigan State University, East Lansing, MI, USA.
Cliff T JohnstonDepartment of Agronomy, Purdue University, West Lafayette, IN, USA.
Hui LiDepartment of Plant, Soil and Microbial Sciences, Michigan State University, East Lansing, MI, USA.
Stephen A BoydDepartment of Plant, Soil and Microbial Sciences, Michigan State University, East Lansing, MI, USA.
Gerben J ZylstraDepartment of Biochemistry & Microbiology, Rutgers University, New Brunswick, NJ, USA.
Donna E FennellDepartment of Environmental Sciences, Rutgers University, New Brunswick, NJ, USA.
Alison M CupplesDepartment of Civil and Environmental Engineering, Michigan State University, East Lansing, MI, USA.
Syed A HashshamDepartment of Civil and Environmental Engineering, Michigan State University, East Lansing, MI, USA. Electronic address: hashsham@egr.msu.edu.

Funding

VOLATILE ORGANIC CONTAMINANTS--QUANTIFYING THEIR MOVEMENT IN THE UNSATURATED ZONEP42ES004911 · NIEHS · MICHIGAN STATE UNIVERSITY · PI Jamie J Bernard · 1989 to 2026
$64.9M
NIEHS NIH HHS P42 ES004911
6 · The paper itself

Abstract

Remediation-focused predictive tools for polychlorinated dibenzo-p-dioxins (PCDD) and polychlorinated dibenzofurans (PCDF) rely on transformation models to evaluate the reduction in total contaminant load and toxic equivalency (TEQ). In this study, a comprehensive model predicting the profiles of PCDD/F congeners and the associated TEQs was developed. The model employs first-order kinetics to describe the transformation of 256 reactions for 75 PCDD congeners and 421 reactions for 135 PCDF congeners. It integrates the growth of anaerobic microbial guilds using Monod kinetics on hydrogen release compounds and stoichiometric growth for Dehalococcoides sp. The effects of temperature, salinity, pH, and availability of vitamin B12 (a cofactor) were also integrated. The PCDD/F congeners model was used to extract the first-order dechlorination rate constants from a number of pure culture and mixed microbial microcosm studies. Simulations for the transformation of PCDD/F congeners at concentrations representative of the Tittabawassee or Saginaw Rivers and watershed in MI, USA were carried out. For a starting TEQ of 5000 ng per kg dry sediment (ppt), the model predicted a decrease in the overall TEQ to below 2000 ppt after 2.6 years and below 250 ppt after ∼21 years. The developed model may be used for extracting rates from microcosm studies and to evaluate the effect of engineering interventions on TEQ reduction.

Indexed as

Dibenzofurans, PolychlorinatedPolychlorinated DibenzodioxinsBenzofuransBiodegradation, EnvironmentalChloroflexiHalogenationHydrogen-Ion ConcentrationKineticsModels, TheoreticalTemperatureVitamin B 12Water Pollutants, ChemicalBenzofuransDibenzofurans, PolychlorinatedPolychlorinated DibenzodioxinsVitamin B 12Water Pollutants, ChemicalBioremediationBiotransformation RatesDibenzo-p-dioxin and DibenzofuransPredictive modelReductive DechlorinationToxic Equivalency

Identifiers

PMID39276747
PMCPMC11608146

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.