Evidence map›Paper›PMID 39276522›Full record

ArticleJournal of clinical anesthesia2024

An automated dispensing cabinet alert influences anesthesia provider medication preparation in a remifentanil waste reduction initiative.

Laura R Wooten, Matthew J Sadlowsky, Jeffrey M Oberhansley, John C Matulis, Nathan J Brinkman, Darrel R Schroeder

Abstract read
In one paragraph

Article in Journal of clinical anesthesia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura R WootenStudent in Doctorate of Nurse Anesthesia Program, Mayo Clinic, Rochester, MN, United States of America.
Matthew J SadlowskyStudent in Doctorate of Nurse Anesthesia Program, Mayo Clinic, Rochester, MN, United States of America.
Jeffrey M OberhansleyAssistant Director for Doctorate of Nurse Anesthesia Program, Mayo Clinic, Rochester, MN, United States of America; Mayo Clinic School of Health Sciences, Mayo Clinic College of Medicine and Science, Rochester, Minnesota; and Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, United States of America.
John C MatulisDivision of Community Internal Medicine, Geriatrics, and Palliative Care, Mayo Clinic, Rochester, MN, United States of America. Electronic address: Matulis.John@mayo.edu.
Nathan J BrinkmanPharmacy Services, Mayo Clinic, Rochester, MN, United States of America.
Darrel R SchroederDivision of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN, United States of America.

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002377
6 · The paper itself

Abstract

STUDY

objectiveTo decrease the occurrence of remifentanil waste of 1 mg or more (1 full vial) by 25 % in our surgical division while maintaining satisfaction of 60 % of providers by using a remifentanil mixing workflow.

designA time series-design quality improvement initiative targeted preventable remifentanil waste. A period of active interventions, followed by a pause and reinstatement of a system intervention, was used to validate its effectiveness.

settingAn academic medical center in the US with 1219 inpatient beds, performing 144,418 surgical cases in 2019 and 127,341 surgical cases in 2020, in 148 operating rooms.

interventionsIndividual- and system-level interventions provided education on the issues of preventable waste, access to a remifentanil dose calculator, and an automated dispensing cabinet (ADC) alert to halt wasteful practice. MEASUREMENTS: Preventable remifentanil waste was identified as disposing of intravenous infusion bags containing 1 mg or more or 1 full vial or more of unused medication. Data were retrieved from ADC reports. A preimplementation and postimplementation survey of anesthesia providers assessed workflow attitudes, perceptions, and satisfaction surrounding remifentanil mixing. MAIN

resultsPreventable remifentanil waste (≥1 mg or ≥ 1 full vial) decreased significantly from 22.0 % of cases using remifentanil at baseline to 16.7 % of cases using remifentanil (odds ratio, 0.71; 95 % CI, 0.60-0.84; P < .001) during the final data collection. Individual-level interventions of education, remifentanil dose calculator, and practice champions did not significantly affect waste while unpaired from the system intervention of the ADC alert.

conclusionsThe implementation of an ADC alert reduced preventable remifentanil waste among anesthesia providers.

Indexed as

Quality ImprovementRemifentanilAcademic Medical CentersAnalgesics, OpioidAnesthetics, IntravenousAutomationDrug CompoundingHumansMedication ErrorsOperating RoomsWorkflowAnalgesics, OpioidAnesthetics, IntravenousRemifentanilChange managementClinical decision supportHealth care costsPharmaceutical technologyQuality improvementRemifentanil

Identifiers

PMID39276522
PMCPMC11588508

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.