Evidence map›Paper›PMID 39276040›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2024

[

X Zhang, J Liu, Q Han, Y Chen, X Ding, X Chen

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

X ZhangThe First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230011, China.
J LiuThe First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230011, China.
Q HanThe First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230011, China.
Y ChenThe First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230011, China.
X DingThe First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230011, China.
X ChenAnhui University of Chinese Medicine, Hefei 230012, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effects of

methodsSD rat models of GA established by injecting monosodium urate into the right ankle joint were treated with saline, colchicine and HQC at low, medium and high doses (

resultsThe rat models of GA showed obvious toe swelling, which reached the peak level at 48 h. HE staining revealed massive inflammatory cell infiltration and synovial tissue hyperplasia. The rat models showed significantly increased expressions of TNF-

conclusionHQC can improve inflammation and correct the imbalance of uric acid and lipid metabolism in GA rats possibly by inhibiting the PTEN/PI3K/AKT signaling pathway.

Indexed as

Arthritis, GoutyDrugs, Chinese HerbalInflammationLipid MetabolismPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktPTEN PhosphohydrolaseRats, Sprague-DawleySignal TransductionUric AcidAnimalsInterleukin-10Interleukin-18MaleRatsTransforming Growth Factor beta1Drugs, Chinese HerbalInterleukin-10Interleukin-18Phosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktPTEN PhosphohydrolasePten protein, ratTransforming Growth Factor beta1Tumor Necrosis Factor-alphaUric Acidgouty arthritisHuangqin Qingrechubi Capsuleinflammationlipid metabolismPTEN/PI3K/AKT signaling pathwayuric acid metabolism

Identifiers

PMID39276040
PMCPMC11378038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.