ArticleNutrients2024
The Relationship between Vitamin D, Inflammatory Markers, and Insulin Resistance in Children.
Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Article
- Correlation of vitamin D levels with TNF-α and IL-6 expression in insulin-resistant type 2 diabetes mellitus patients.Scientific reports · 2026Article
- Vitamin D and Health Outcomes: State-of-the-Art Review of Triangulated Evidence and Ongoing Controversies.Current nutrition reports · 2026Review
- Article
- Article
- Association between vitamin D and inflammatory markers in the Chinese healthy adult population: a cross-sectional study.Food & nutrition research · 2026Article
- Evaluation of novel inflammatory biomarkers in overweight, obese, and morbidly obese children: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Association between serum vitamin D levels and cardiovascular disease risk in patients with hyperuricemia: A cross-sectional study.PloS one · 2026Article
- The potential hematological features of children with spastic cerebral palsy in China: a retrospective multidimensional data analysis based on routine hematological indicators.Frontiers in pediatrics · 2026Article
- Article
- Causal Relationship Between Various Vitamins and Different Diabetic Complications: A Mendelian Randomization Study.Food science & nutrition · 2025Article
- Mediating role of inflammatory markers (NLR, PLR, SII, SIRI) in the association between 25(OH)D deficiency and obesity in children and adolescents.Journal of health, population, and nutrition · 2025Article
- The relationship between novel inflammatory markers SII, SIRI, MHR, UHR and insulin resistance in patients with type 2 diabetes: based on a retrospective analysis.Frontiers in endocrinology · 2025Article
- Exploring the Interplay Between Vitamin D and Metabolic Parameters in Pediatric Obesity: Toward Early Biomarker Detection.Journal of nutrition and metabolism · 2025Article
- Vitamin D levels and platelet status in healthy children and adolescent.Frontiers in nutrition · 2025Article
- Preoperative SII Can Predict Postoperative Recurrence and Serious Complications in Patients with Hepatolithiasis.Journal of inflammation research · 2025Article
- The Relationship Between Novel Inflammatory Markers and Serum 25-Hydroxyvitamin D Among US Adults.Immunity, inflammation and disease · 2025Article
- Associations of systemic inflammation and systemic immune inflammation with serum uric acid concentration and hyperuricemia risk: the mediating effect of body mass index.Frontiers in endocrinology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn this study, we investigated 25-hydroxyvitamin D (25(OH)D, vitamin D), inflammatory hematologic ratios such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation index (SII), monocyte/HDL-C ratio (MHR) and plasma atherogenic index (PAI) and possible relationships with insulin resistance (IR) in children.
methodsA total of 210 individuals, including 96 children with IR and 114 children without IR, aged 6-18 years, who were admitted to the Pediatric Endocrinology Outpatient Clinic at Medicine Hospital, Istanbul Atlas University were included in our study.
resultCompared to patients without IR, NLR, PLR, SII, and MHR were significantly higher in patients with IR. Fasting insulin, PAI, homeostasis model assessment of insulin resistance (HOMA-IR), and HOMA-β were significantly higher and quantitative insulin sensitivity check index (QUICKI) was considerably lower in patients with IR compared to those without IR. NLR, SII, and MHR were lower in normal vitamin D groups than the others (
conclusionsWe found that vitamin D deficiency in childhood is related to increased levels of circulating inflammatory markers (NLR, PLR, MHR, PAI), IR, and decreased insulin sensitivity. According to our results, supplementation of vitamin D may be beneficial in averting IR and enhanced systemic inflammation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.